alexa Fei Ye | Mount Sinai School of Medicine
ISSN-2155-9929

Journal of Molecular Biomarkers & Diagnosis
Open Access

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Fei Ye

Fei Ye Fei Ye
Department of Pathology
Mount Sinai School of Medicine
USA
Biography

Dr. Ye’s presently working in the department of Pathology, Mount Sinai School of Mediicne, USA. Research work had been focus on plant-derived agents and their anti-cancer activity and their molecular mechanism since 1995.

Research Interest

Dr. Ye’s research work had been focus on plant-derived agents and their anti-cancer activity and their molecular mechanism since 1995. One such drug, SBX, can inhibit NSCLC cell growth in vitro and in animals, and SBX directly targets the ERK pathway. More significantly, SBX is more potent and much tolerable than carboplatin, a most effective drug for NSCLC. Combination of SBX with carboplatin can synergistically increase the potency of their anticancer activity, probably acting cooperatively on different anti-proliferation mechanisms. Dr. Ye Also has a strong interest in drug and diagnostic marker discovery. In order for searching biomarkers and drugable targets for cancer diagnosis and treatment, Dr. Ye recently developed a novel Protein Pathway Array Technology (https://www.celldiv.com/content/4/1/20). The Pathway Array technology is an innovative proteomic assay that allows screen globally the changes in protein expression and phosphorylation. The focus of Protein Pathway Array is to determine the signaling networks that related to proliferation, apoptosis, angiogenesis, invasion and metastasis. Using this technology, Dr. Ye and her group identified several promising protein biomarkers for cancer diagnosis, molecular staging and prognosis.

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Publications

Multiple Literacies for Individuals who are Blind or with Visual Impairment: A Quantitative Comparison on Print, Braille, and Auditory Literacies
Ye Wang, Shariffa Khalid Qais Al-Said and Feifei Ye
Research Article: Int J Sch Cog Psychol 2017, 4: 193
DOI: 10.4172/2469-9837.1000193
 
Detection of Mitochondrial Mutations in Cancer by Next Generation Sequencing
Fei Ye, David C, Samuels and Yan Guo
Review Article: Next Generat Sequenc & Applic 2014,1: 102
DOI: 10.4172/2469-9853.1000102
 
Proteomic Approaches for Profiling Cancer Signaling Pathways
Fei Ye and David Y. Zhang
Editorial: J Mol Biomark Diagn 2012, 3: e104
DOI: 10.4172/2155-9929.1000e104
 
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