alexa HARDIK CHANDASANA | University of Florida
ISSN: 2157-7609

Journal of Drug Metabolism & Toxicology
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HARDIK CHANDASANA

HARDIK CHANDASANA HARDIK CHANDASANA Professor Department of Pharmaceutics, University of Florida USA Phone no: +1-352-213-9228
Biography

Well experienced in conducting analytical DMPK activities like in vitro Plasma stability, Metabolic stability with liver microsomes and Hepatocytes, Reaction phenotyping, Plasma protein binding, CYP inhibition assays for IC 50 value, RBC Partitioning, Drug stability in SGF and SIF, Metabolite identification and other analytical studies such as solubility, chemical stability, logP, logD value measurement etc . • Preclinical formulation for PK studies. • Bioanalytical method development and validation ( Plasma, Tears, Vaginal fluids ,Tissues etc.) • Animal Handling Techniques.(Rat, Mice, Hamster and Rabbit). • Experience in preclinical (Mice, Rat, Hamster and Rabbit) and clinical (healthy volunteers) ADME/pharmacokinetic evaluation of NCEs/drugs and their formulations • Preclinical tissue distribution studies. • Drug-drug, herb-drug and food-drug interaction studies for suggesting benefits (as potential combination)/risks of the same in therapies. • Preclinical and clinical data analysis, modeling, biostatistics and IVIVC. Dose predictions and PBPK modeling for human pharmacokinetic prediction. Conduction and data analysis of bioavailability, bioequivalence and food effect studies. • Microdialysis technique to determine free drug concentration

Research Interest

Drug Metabolism and Pharmacokinetics Division

Publications

Challenges Associated with the Quantification of Tear Fluids
Hardik Chandasana
Editorial: J Bioequiv Availab
DOI: 10.4172/jbb.10000e73
 
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