alexa Ivan Gout | University College London
ISSN: 2476-2261

Journal of Oncology Translational Research
Open Access

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Ivan Gout

Ivan Gout Ivan Gout
Department of Structural and Molecular Biology
University College London

Graduated as an MD at Lviv State Medical University (Ukraine) in 1983 with a great passion to become a surgeon in oncology. Thinking that a PhD in experimental oncology would help to realize his dream, he obtained doctorate at the Institute of Experimental Oncology, National Academy of Sciences of Ukraine in 1987. A fellowship from the International Agency for Research on Cancer (IARC) taken him even further from clinical oncology and also from Ukraine. He arrived in London on the first wave of perestroika and began post-doctoral training in Jim Woodgett's laboratory at the Ludwig Institute for Cancer Research (UCL Branch). Subsequently, he worked in Mike Waterfield's laboratory at the same Institute studying signal transduction via the PI3 kinase pathway. In 1996, he started his own group at the Ludwig Institute for Cancer Research, focusing on the regulation of growth via the S6 kinase pathway. Since 2003, he has been a Professor in the Department of Biochemistry at UCL – now renamed Structural and Molecular Biology, where he had an active research group working on signal transduction and cellular metabolism in health and disease. He had a strong research (113 papers in peer-reviewed journals, H-Index 52) and patent (10 world-wide patents) portfolio and run two drug discovery programs aimed at developing small molecule inhibitors, targeting ribosomal S6 kinase and Aurora A kinase.

Research Interest

Signal transduction, Cancer Biochemistry, Gene expression, Enzyme inhibition

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