Cloning & Transgenesis
Open Access

Karen W. Y. Yuen

Biography

Dr. Karen W. Y. Yuen completed her PhD in the Department of Medical Genetics at the University of British Columbia, Canada, studying chromosome instability in the budding yeast Saccharomyces cerevisiae and human cancers. She then pursued her post-doctoral training as a Croucher Fellow at the Ludwig Institute for Cancer Research and the University of California, San Diego, USA, studying centromere and kinetochore formation and propagation in Caenorhabditis elegans. Dr. Yuen is currently an Assistant Professor in the School of Biological Science at the University of Hong Kong. Dr. Yuen has received the Hong Kong Research Grants Council Early Career Award. She is now focusing on cellular mechanisms involved in chromosome segregation. She is also interested in the development of accurately segregating artificial chromosomes.

Research Interest

Dr. Yuen’s research is focused on cellular mechanisms involved in chromosome segregation, including centromere and kinetochore function, sister chromatid cohesion, and epigenetic regulation. She is interested in the mechanism of de novo centromere establishment on chromosomes in cancers, chromosome rearrangements, evolution and on artificial chromosomes. She is also involved in the development of accurately segregating artificial chromosomes for applications as cloning vectors and gene therapies.