alexa Marek Malecki | University of Wisconsin
ISSN: 2157-7633

Journal of Stem Cell Research & Therapy
Open Access

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Marek Malecki

Marek Malecki Editor-in-Chief
Marek Malecki, MD PhD
President
Genetic and Biomolecular Engineering
PBMEF, San Francisco, USA
Biography

Marek Malecki MD PhD is President of Phoenix Biomolecular Engineering Foundation, Chief Executive Officer of the Center for Molecular Medicine, and Visiting Professor at the University of Wisconsin. He earned MD degree at the Medical Academy, Poznan followed by Residency/Fellowship in Molecular Medicine in Rigshospitalet, Copenhagen. He earned PhD at the National Academy of Sciences, Warsaw followed by the postdoctoral fellowships in molecular biology at the Austrian Academy of Sciences, Karolinska Institutet, Stockholm, Salzburg and Vienna, ETH, Zurich, Utrecht University Medical School, Utrecht, Cancer Center, Vienna, Cancer Center, Amsterdam, Biozentrum, Basel. Dr Malecki developed a novel technology to identify and isolate single living pluripotent stem cells followed by their clonal expansion and molecular profiling including sequencing their proteomes, transcriptomes, and genomes. This technology serves also for reprogramming the stem cells for their use as the vectors in gene therapy of cancer. The technology, protected by the US and WIPO, is currently streamlined to clinical trials. He is the first author on the peer-reviewed articles. He is often an invited speaker and courses’ faculty at the international professional conferences. Dr Malecki is Editor in Chief of the Journal of Genetic Syndromes and Gene Therapy and Member of the Editorial Boards for many high-impact professional journals. He is the member of the American Medical Association, American Association of Human Genetics, American Antibody Society, Southern California Biotechnology Council, and Rho Chi Honor Society for Excellence in Teaching and as the Faculty Role Model.

Research Interest

cancers of ovaries, cancers of testes, cancer stem cells (CSC), circulating tumor cells (CTCs), genetic disorders, iatrogenic genetic mutations, gene therapy, targeted gene delivery, fertility sparing therapy, biobanking, in vitro fertilization.

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Publications

Novel Approach for Designing Supportive Care in Genetic Disorders of Gastrointestinal Tract: Three-Dimensional Polymer Model of Nutritional Therapies in Cystic Fibrosis, Ulcerative Colitis, and Crohn`s Disease
Paul Zarogoulidis, Ioannis Kioumis, Theodora Tsiouda, Nikolaos Pezirkianidis, Christos Ritzoulis, Haidong Huang, Wolfgang Hohenforst-Schmidt, Dionysios Spyratos, Konstantinos Porpodis, Georgia Pitsiou, Nikolaos Pezirkianidis, Sofia Lampaki, John Organtzis, Konstantinos Zarogoulidis, Bianca Malecki, Marek Malecki
Research Article: J Nanomedine Biotherapeutic Discov 2014, 4: 128
DOI: 10.4172/2155-983X.1000128
 
Safeguarding Stem Cell-Based Regenerative Therapy against Iatrogenic Cancerogenesis: Transgenic Expression of DNASE1, DNASE1L3, DNASE2,DFFB Controlled By POLA1 Promoter in Proliferating and Directed Differentiation Resisting Human Autologous Pluripotent Induced Stem Cells Leads to their Death
Marek Malecki, Christine LaVanne, Dominique Alhambra, Chaitanya Dodivenaka, Sarah Nagel and Raf Malecki
Research Article: J Stem Cell Res Ther 2013, S9-005
DOI: 10.4172/2157-7633.S9-005
 
Eradication of Human Ovarian Cancer Cells by Transgenic Expression of Recombinant DNASE1, DNASE1L3, DNASE2, and DFFB Controlled by EGFR Promoter: Novel Strategy for Targeted Therapy of Cancer?
Marek Malecki, Jessica Dahlke, Melissa Haig, Lynn Wohlwend and Raf Malecki
Research Article: J Genet Syndr Gene Ther 2013, 4: 152
DOI: 10.4172/2157-7412.1000152
 
Suicide Gene Therapy for Cancer – Current Strategies
Paul Zarogoulidis, Kaid Darwiche, Antonios Sakkas, Lonny Yarmus, Haidong Huang, Qiang Li, Lutz Freitag, Konstantinos Zarogoulidis and Marek Malecki
Review Article: J Genet Syndr Gene Ther 2013, 4: 139
DOI: 10.4172/2157-7412.1000139
 
Improved Targeting and Enhanced Retention of the Human, Autologous, Fibroblast-Derived, Induced, Pluripotent Stem Cells to the Sarcomeres of the Infarcted Myocardium with the Aid of the Bioengineered, Heterospecific, Tetravalent Antibodies
Marek Malecki
Research Article: J Stem Cell Res Ther 2013, 3:138
DOI: 10.4172/2157-7633.1000138
 
TRA-1-60+, SSEA-4+, POU5F1+, SOX2+, NANOG+ Clones of Pluripotent Stem Cells in the Embryonal Carcinomas of the Testes
Marek Malecki, Xenia Tombokan, Mark Anderson, Raf Malecki and Michael Beauchaine
Research Article: J Stem Cell Res Ther 2013, 3:134
DOI: 10.4172/2157-7633.1000134
 
Frontiers in Suicide Gene Therapy of Cancer
Marek Malecki
Review Article: J Genet Syndr Gene Ther 2012, 3:119
DOI: 10.4172/2157-7412.1000119
 
TRA-1-60+, SSEA-4+, Oct4A+, Nanog+ Clones of Pluripotent Stem Cells in the Embryonal Carcinomas of the Ovaries
Marek Malecki, Mark Anderson, Michael Beauchaine, Songwon Seo, Xenia Tombokan, Raf Malecki
Research Article: J Stem Cell Res Ther 2012, 2:130
DOI: 10.4172/2157-7633.1000130
 
Nuclear Routing Networks Span between Nuclear Pore Complexes and Genomic DNA to Guide Nucleoplasmic Trafficking of Biomolecules
Marek Malecki, Bianca Malecki
Research Article: J Fertiliz In Vitro 2012, 2:112
DOI: 10.4172/2165-7491.1000112
 
Cancer Suicide Gene Therapy
Marek Malecki
Editorial: J Genet Syndr Gene Ther 2012, 3:e114
DOI: 10.4172/2157-7412.1000e114
 
Routing of Biomolecules and Transgenes' Vectors in Nuclei of Oocytes
Marek Malecki and Bianca Malecki
Research Article: J Fertiliz In Vitro 2012, 2:108
DOI: 10.4172/2165-7491.1000108
 
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