alexa Mario Arciello | Sapienza university of Rome
ISSN: 2167-7956

Journal of Biomolecular Research & Therapeutics
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Mario Arciello

Mario Arciello
Assistant Professor
Department of Internal Medicine and Medical Specialties
"Sapienza" University of Rome

Dr. Mario Arciello is a researcher of “Sapienza” University of Rome. He’s a biologist graduated in 2004 at “Tor Vergata” University of Rome with an experimental thesis in Biochemistry. He has focused its early scientific activity on the study of copper homeostasis alteration in cultured neuronal cells models for Menkes and Wilson diseases, two inherited diseases paradigm of this condition, mainly on its role in the mitochondrial dysfunctions and oxidative stress occurrence. His acquired knowledge led him to study these topics also in the etiopathogenesis of neurodegenerative disorders like Alzheimer’s disease (AD) and the familial form of Amyotrophic Lateral Sclerosis (fALS). After the achievement of the PhD degree in Cellular and Molecular Biology in the 2009 at “Tor Vergata” University of Rome, he has focused its scientific research interests on the molecular pathogenesis of liver diseases, mainly hepatitis due to C virus (HCV) infection and non-alcoholic fatty liver disease (NAFLD). In particular, his investigation topics are the role of oxidative stress, mitochondrial dysfunctions, morphogens and tumor suppressors signaling pathways in liver diseases onset and progression. Dr Arciello is member of Associazione Italiana per lo Studio del Fegato (AISF) and of European Association for the Study of the Liver (EASL).

Research Interest

Copper homeostasis
Menkes’ and Wilson’s Diseases.
Liver diseases (e.g. NAFLD and HCV infection)
Metabolic diseases
Oxidative stress and antioxidant defenses
Lipid metabolism
Glucose metabolism

Global Speakers in the subject

Global Experts in the subject


The Near Future of HCV Treatment: Supplementary Treatments against Oxidative Stress will be still useful?
Mario Arciello
Editorial: J Biomol Res Ther 2014, 3: e131
DOI: 10.4172/2167-7956.1000e131
Exocycilic DNA Adducts in a Murine Model of Non-alcoholic Steatohepatitis
Marco ME Peluso, Armelle Munnia, Mirko Tarocchi, Mario Arciello, Clara Balsano, Roger W Giese and Andrea Galli
Research Article: J Carcinog Mutagen 2014, S3-003
DOI: 10.4172/2157-2518.S3-003
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