alexa Editor - Qiao Li | University of Michigan | 5255
ISSN: 2161-1076

Surgery: Current Research
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Qiao Li

Qiao Li Qiao Li
Senior Editor
University of Michigan Medical Center
USA
Biography

Qiao Li, Ph.D. is a Research Assistant Professor in the Section of General Surgery in the Surgery Department. Dr. Li received his bachelor′s degree from Wuhan University in Wuhan, China and a master′s degree from the Chinese Academy of Sciences. He received his Ph.D. in Immunology and Biological Sciences from Wayne State University in Detroit, Michigan. Dr. Li completed his postgraduate training in Molecular Biology and Cell Biology from the Brigham and Women's Hospital and Dana-Farber Cancer Institute at Harvard Medical School in Boston, Massachusetts. He was an Assistant Professor of Biology at Wuhan University from 1985 through 1989. Dr. Li joined the faculty at the University of Michigan in 1997.
Dr. Li′s research focuses on the generation of tumor-reactive T cells for the adoptive immunotherapy of cancer. To sensitize/induce tumor-reactive T cells in vivo, lymph node cells are primed utilizing as vaccines the genetically modified tumor cells, tumor cells admixed with bacterial adjutants, or antigen/antigen presenting cells. In order to optimize the methods that are capable of expanding lymphoid cells in vitro while maintaining or augmenting their antitumor reactivity, Dr. Li′s research effort centers on developing new strategies for T cell activation /expansion using monoclonal antibodies and recombinant cytokines. The investigation and optimization of T cell activation/expansion conditions involves primary CD3/IL-2 signaling as well as co-stimulatory signals for T cell proliferation and differentiation, such as CD28, CD40L, and 4-1BB. Dr. Li′s research effort is also devoted to the identification and characterization of tumor-specific T cell subsets. This issue is addressed by defining the specific antitumor reactivity of CD4+ cells or CD8+ cells, differentiating Th1/Tc1 versus Th2/Tc2 cytokine responses, studying molecules markers on T cells or Vb usage by T cell subsets or by isolating and characterizing tumor associated antigens.

Research Interest

Tumor Immunology and Cancer Immunotherapy.

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Publications

Development and Application of Cancer Stem Cell-Targeted Vaccine in Cancer Immunotherapy
Qiao Li, Shiang Huang, Ming Lin, Max S. Wicha and Alfred E Chang
Short Communication: J Vaccines Vaccin 2017, 8:371
DOI: 10.4172/2157-7560.1000371
 
Identification and Characterization of a New Enterobacter Onion Bulb Decay Caused by Lelliottia amnigena in China
Shiyin Liu, Yingxin Tang, Dechen Wang, Nuoqiao Lin and Jianuan Zhou
Research Article: Appli Micro Open Access
DOI: 10.4172/2471-9315.1000114
 
Apolipoprotein E Mimetic Promotes Functional and Histological Recovery in Lysolecithin-Induced Spinal Cord Demyelination in Mice
Zhen Gu, Fengqiao Li, Yi Ping Zhang, Lisa B.E. Shields, Xiaoling Hu, Yiyan Zheng, Panpan Yu, Yongjie Zhang, Jun Cai, Michael P. Vitek, and Christopher B. Shields
Research Article: J Neurol Neurophysiol 2013, S12:010
DOI: 10.4172/2155-9562.S12-010
 
Regulation of Myf5 Early Enhancer by Histone Acetyltransferase p300 during Stem Cell Differentiation
Tanja Francetic, Melanie Le May, Munerah Hamed, Hymn Mach, David Meyers, Philip A Cole, Jihong Chen and Qiao Li
Research Article: Mol Biol 2012, 1:1
DOI: 10.4172/2168-9547.1000103
 
Transcriptomics Evaluation of Hexavalent Chromium Toxicity in Human Dermal Fibroblasts
Rajendran Sellamuthu, Christina Umbright, Rebecca Chapman, Stephen Leonard, Shengqiao Li, Michael Kashon and Pius Joseph
Review Article: J Carcinog Mutagen 2011, 2:116
DOI: 10.4172/2157-2518.1000116
 
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