alexa Takato Hiranita | University of Colorado at Boulder
ISSN: 2329-6488

Journal of Alcoholism & Drug Dependence
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Takato Hiranita

Takato Hiranita Editor-in-Chief
Dr. Takato Hiranita
Visiting Scientist
Division of Neurotoxicology,
National Center for Toxicological Research
Food and Drug Administration
3900 NCTR Road (HFT-132, building 50, room 150)
Jefferson, AR 72079-9501
USA
Tel: 443/740-2556
Biography

He earned his Ph.D. in Pharmacology: Pharmaceutical Sciences at Kyushu University, Japan, under the supervision of Dr. Tsuneyuki Yamamoto and has been a postdoctoral research fellow in the laboratory of Dr. Jonathan L. Katz at the National Institute on Drug Abuse (NIDA). He is currently a research associate in the laboratory of Dr. Linda R. Watkins at University of Colorado at Boulder, and conducting experiments at NIDA for a research collaboration under the supervision of Dr. Watkins. Using drug self-administration procedures in rodents and primates and drug discrimination procedures in rodents he has examined novel dopamine uptake inhibitors as potential medications to treat cocaine abuse. In addition, he found that cocaine self-administration is decreased by combined treatment with the dopamine uptake inhibitors and antagonists at the σ receptor which may shed light on the mechanisms underlying the intractability of stimulant abuse.

Research Interest

His research interests include Dual inhibition hypothesis as a target for cocaine abuse medications, dual σR/DAT inhibitions, Role of specific receptors in food reinforcement mechanisms and Role of The ATP receptor subtypes in the reinforcing effects of drugs of abuse.

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Publications

Importance of Substrate-Coupled Proton Antiport by the Vesicular Monoamine Transporter in the Actions of Amphetamines in Drosophila Brain
Takato Hiranita and Zachary Freyberg
Editorial: J Alcohol Drug Depend 2016, 4: e136
DOI: 10.4172/2329-6488.1000e136
 
Lack of Effects of Toll-Like Receptor 4 Antagonists on the Reinforcing Effects of Cocaine and Remifentanil
Takato Hiranita
Editorial: J Alcohol Drug Depend 2016, 4: e135
DOI: 10.4172/2329-6488.1000e135
 
DAT Conformation Does Not Predict the Ability of Atypical Dopamine Uptake Inhibitors to Substitute for Cocaine
Takato Hiranita
Editorial: J Alcohol Drug Depend 2016, 4: e132
DOI: 10.4172/2329-6488.1000e132
 
Identification of Antagonists Selective for Sigma Receptor Subtypes that are Active In vivo
Takato Hiranita
Editorial: J Alcohol Drug Depend 2016, 4: e131
DOI: 10.4172/2329-6488.1000e131
 
Identification of the Sigma-2 Receptor: Distinct from the Progesterone Receptor Membrane Component 1 (PGRMC1)
Takato Hiranita
Editorial: J Alcohol Drug Depend, 4: e130
DOI: 10.4172/2329-6488.1000e130
 
Trans-9-Tetrahydrocannabinol-Like Discriminative-Stimulus Effects of Gabapentin in Cannabis Users
Takato Hiranita
Editorial: J Alcohol Drug Depend 2016, 4: e129
DOI: 10.4172/2329-6488.1000e129
 
Self-Administration of JWH-018 A Synthetic Cannabinoid in Experimentally Naïve Rats
Takato Hiranita
Editorial: J Alcohol Drug Depend 2015, 3: e128
DOI: 10.4172/2329-6488.1000e128
 
Preclinical Efficacy of Novel Vesicular Monoamine Transporter 2 Inhibitors as Antagonists of d-Methamphetamine Self-Administration in Rats
Takato Hiranita
Editorial: J Alcohol Drug Depend 2015, 3:e127
DOI: 10.4172/2329-6488.1000e127
 
Self-Administration of an Endogenous Cannabinoid 2-Arachidonoylglycerol in Experimentally Naïve Rats
Takato Hiranita
Editorial: J Alcohol Drug Depend 2015, 3:e126
DOI: 10.4172/2329-6488.1000e126
 
Cocaine Antagonists; Studies on Cocaine Self-Administration
Takato Hiranita
Editorial: J Alcohol Drug Depend 2015, 3:e125
DOI: 10.4172/2329-6488.1000e125
 
Differential Roles for Dopamine D1-Like and D2-Like Receptors in Mediating the Reinforcing Effects of Cocaine: Convergent Evidence from Pharmacological and Genetic Studies
Takato Hiranita and Gregory T Collins
Editorial: J Alcohol Drug Depend 2015, 3:e124
DOI: 10.4172/2329-6488.1000e124
 
Trace Amine-Associated Receptor Type 1 as A Target for The Development of Treatments for Stimulant Abuse
Takato Hiranita
Editorial: J Alcohol Drug Depend 2015, 3:e122
DOI: 10.4172/2329-6488.1000e122
 
Medications Discovery: Importance of Assessment of Drug Self Administration Dose-Effect Curves
Takato Hiranita
Editorial: J Alcohol Drug Depend 2015, 3:e121
DOI: 10.4172/2329-6488.1000e121
 
In Vivo Significance of In Vitro Studies on G-Protein-Coupled Receptor Heteromers
Takato Hiranita
Editorial: J Alcohol Drug Depend 2014, 3:e120
DOI: 10.4172/2329-6488.1000e120
 
Role of the σRs for Development of Medications
Takato Hiranita
Editorial: J Alcohol Drug Depend 2014, 2:e109
DOI: 10.4172/2329-6488.1000e109
 
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