alexa Yong Li | The University of Texas Medical School
ISSN: 2329-8847

Journal of Aging Science
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Yong Li

Yong Li Yong Li
The University of Texas Medical School

Dr. Yong Li, is a Professor within the Department of Pediatric Surgery at the University of Texas, School of Medicine at Houston. He also is appointed a key faculty in the Center for Stem Cell and Regenerative Medicine at the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM) at The University of Texas Health Science Center at Houston. Dr. Li is an expert in the field of stem cell and fibrosis study in regenerative medicine. His recently study move to tissue/cell dedifferentiation process by using musculoskeletal and neuronal system of mammals and related aging research.Dr. Li has published over 70 refereed journal articles and 7 book chapters. Dr. Li is recognized as aleader in two scientific fields which include dedifferentiation related stem cell studies and fibrosis studies in tissue biomedical engineering.

Current Research

• Children’s Regenerative Medicine

• Dedifferentiation and Stem Cell Populations and Aging

• Adult Embryonic Potential Stem Cells and Application in Aging

• Fibrosis and Prevention Studies

Research Interest

My primary research focuses on three major areas of study: 1) exploring the properties of the dedifferentiation/transformation of terminally differentiated cells into various stem cells include aged donors; 2) studying the processes involved with fibrous scar formation and prevention in the injured and diseased tissues of the neuron and musculoskeletal system; and 3) Bioengineering to build 3D soft tissues (muscle & tendon) to repair wound defects with scarless healing. The laboratory is also interested in translational study and clinical application of stem cells and engineered tissue for treating congenital diseases and traumatic injuries. We have also set up classic amphibian models of tissue regeneration; newts and salamanders can rebuild most missing body parts such as limbs, liver, brain and heart after amputation or injury, and no age limitation. We will investigate the molecule and cellular dedifferentiation process for increasing the stem cell population and methods of preventing fibrotic scar tissue formation during mammalian wound healing. Our expectation is to transfer our learning from amphibian regenerative models to enlarge stem cell pool for regenerative medicine applications, and to build various functional human tissues/organs for human patients’ demand.



Effects Research of Environmental Hormone BPA and PAEs on the Expression of HSP70-9 Gene in Spinacia oleracea
Wenxue Jia and Peiyong Liu
Research Article: J Environ Anal Toxicol 2017, 7:438
DOI: 10.4172/2161-0525.1000438
Association Studies of DRD2 and COMT Gene Polymorphisms with Risperidone-induced Amenorrhea in Female Schizophrenia Patients
Chengye Hou, Jintian Xu, Jing Yan, Zhenguo Zhao, Yan Sun, Zhiyong Li, Yang Shen, Yichen Huang, Songnian Hu and Ying Liang
Research Article: J Health Edu Res Dev 2017, 5: 213
DOI: 10.4172/2380-5439.1000213
Prevalence and Factors Associated With Decreased Bone Mineral Density in Young and Middle-Aged Male Schizophrenic Patients
Yang Shen, Zhiyong Li, Yichen Huang, Jing Yan and Ying Liang
Research Article: J Osteopor Phys Act 2017, 5: 189
DOI: 10.4172/2329-9509.1000189
The GC/TOFMS based Serum Metabolomics in Rats with Depression-like Behavior after Exposure and Re-exposure to Chronic Unpredictable Mild Stress
Zhiguo Li, Shuguang Yang , Changqiang Zhu, Jianhua Chen, Xinghua Ding , Yong Liu , Liang Jiao , Fangting Dong* and Shaojun Liu *
Research Article: J Psychiatry
DOI: 10.4172/2378-5756.1000396
Coexistence of Aedes aegypti and Aedes albopictus in Jinghong City, Yunnan Province: A Survey of Aedes aegypti Invasion
Yu-Hong Guo, Sheng-Jie Lai, Qiang Huang, Dong-Sheng Ren, Jian-Hong Zou , Qi-Yong Liu, Huai-qing Zhang
Research Article: J Trop Dis
DOI: 10.4172/2329-891X.1000227
Nitrous Oxide Emissions From Household Vegetable Fields in The Rural Residential Areas of Hilly Subtropical Central China
Xiaoqing Fu, Yong Li, Yi Wang, Jianlin Shen, Runlin Xiao, Dan Chen and Jinshui Wu
Research Article: Environ Pollut Climate Change 2016, 1:1
DOI: 10.4172/2573-458X.1000103
Phase II Study Evaluating the Effect of Concomitant Ramucirumab on the Pharmacokinetics of Docetaxel in Patients with Advanced Solid Tumors
Mark N Stein*, Laura Q M Chow, David C Smith, Dale R Shepard, Ding Wan, John Powderly, Archana Chaudhary, Yong Lin and Ling Gao
Research Article: Clin Pharmacol Biopharm 2016, 5:161
DOI: 10.4172/2167-065X.1000161
Frailty and Potential Biomarkers in Aging
Jessica L. Lee and Yong Li
Editorial: J Aging Sci 2016, 4: e121
DOI: 10.4172/2329-8847.1000e121
Benefits of Exercise for the Prevention of Diseases in the Premature Aging
Robert Lugo, Carmel B. Dyer and Yong Li
Review Article: J Aging Sci 2016, 4: 154
DOI: 10.4172/2329-8847.1000154
Identification of NaHCO3 Stress Responsive Proteins in Dunaliella salina HTBS using iTRAQ-based Analysis
Yue Zhao, Yuyong Hou, Zhiyong Liu, Shulin Chen and Fangjian Chen
Research Article: J Proteomics Bioinform Vol.9: 137-143
DOI: 10.4172/jpb.1000399
Two Novel Curcumin Analogues Induced Reactive Oxygen Species Generation and Mitochondrial-Related Apoptosis in Human Breast Cancer MCF - 7 Cells
Shuyue Luo, Qingyong Li, Jian Chen and Wengchao Wang
Research Article: J App Pharm 2016, 8: 215
DOI: 10.4172/1920-4159.1000215
Histone Deacetylase Inhibitors can Repress Proliferation and Induce Apoptosis in Gingiva Progenitor Cells from Idiopathic Gingival Fibromatosis
Zhi Jia, Chunyue Feng, Yingchenyao Wang, Jingkun Li, Tingting Zhang, Jian Zhang and Dayong Liu
Research Article: J Stem Cell Res Ther 2016, 6:327
DOI: 10.4172/2157-7633.1000327
Detection and quantification of Uromyces setariae-italicae in foxtail millet by a real-time PCR assay
Nan Wang, Zhiping Dong, Hui Bai, Li Dong, Yongfang Wang, Jianzhang Quan, Lei Liu, Zhiyong Li
Research Article: Journal of Microbiology and Biotechnology
Optimization of Two-Dimensional Gel Electrophoresis Analysis of Chinese Cabbage (Brassica rapa L. Ssp. Pekinensis) Buds
Xue Zhou, Ruiqin Ji, Zhiyong Liu and Hui Feng
Research Article: Horticulture 2015, 2: 146
DOI: 10.4172/2376-0354.1000146
Nursing care for esophageal cancer patients receiving radiation therapy in China: A review of the published literature
Fengxia Liu, Cuizhi Geng, Yong Li, Ruili Zhang, Lin Kang and Weikuan Gu
Review Article: J Nurs Care 2015, 4:243
DOI: 10.4172/2167-1168.1000243
Redox Sensitive Nanoparticles with Disulfide Bond Linked Sheddable Shell for Intracellular Drug Delivery
Huiyun Wen and Yongyong Li
Review Article: Med Chem (Los Angeles) 2014, 4: 748
DOI: 10.4172/2161-0444.1000225
Single Polymer-drug Conjugate Carrying Two Drugs for Fixed-dose Codelivery
Yan Li, Haiqing Dong, Xuequan Li, Donglu Shi and Yongyong Li
Research Article: Med Chem (Los Angeles) 2014, 4: 676
DOI: 10.4172/2161-0444.1000211
Metabolic Enzymes: The Novel Targets for Cancer Stem Cells
Yaoyu Chen, Peng Li and Jianyong Li
Commentary: J Stem Cell Res Ther 2014, 4:197
DOI: 10.4172/2157-7633.1000197
Six-Month Outcomes for Patients Attending a Substance Abuse Clinic in Hong Kong: A Retrospective Study
Chieh Grace Lau, Wai Kwong Tang, Wei Hao, Yong Lin, Hua Jun Liang, Alan Tang and Gabor Sandor Ungvari
Research Article: J Alcohol Drug Depend 2014, 2:155
DOI: 10.4172/2329-6488.1000155
Asymptomatic Infection of Borrelia burgdorferi in Xinjiang, China
Yuhui Tan, Qin Hao, Kanglin Wan, Yong Liu, He Sun, Luhai Yu, Yuhan Zhang, Hui Dang, Mingyuan Wang, Yi Zhu1, Hetaer Mo, Siya A, Jiang Long, Hongyan Li, Yinuer Ma and Qin Li
Research Article: J Bacteriol Parasitol 2012, 3:145
DOI: 10.4172/2155-9597.1000145
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