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Vindhya Palagani

Maiden Name: Vindhya Palagani
Researcher
Working address: Department of Pathology, Medical College of Wisconsin Cancer Center, 8701 Watertown Plank Road, TBRC-4, Milwaukee, WI-53226, USA

 
Biography

PhD in Biology (2010-2013)
Started PhD in April 2010 at Hannover medical school, Hannover, Germany. Later relocated along with the group to Medizinische Universitätsklinik, Tuebingen.

Master of Science in Molecular Biology (2008-2009)
• Principal Subjects: Applied biotechnology, genetic engineering, immunology, recombinant DNA technology and molecular microbiology.
• Thesis: Characterization of colonic inflammation and immune cells in the pathogenesis of autoimmune diabetes (performed at Department of Medical Microbiology and Immunology University of Turku; Turku, Finland)
• University of Skovde, Skovde, Sweden.

Bachelor of Technology in Biotechnology (2003-2007)
• Principal subjects: Fundamental genetics, molecular biology, structural biochemistry, Genetic engineering, microbiology, cell biology, basic tumor biology, immunology, organic chemistry, and basic neurobiology.
• Thesis: Polymorphism of eNOS gene (Bioserve Biotechnologies, Hyderabad, INDIA).
• Jawharlal Nehru Technological University, Hyderabad, India.

Research Interest

 Analysis of Jak2-Stat5a/b signaling in enzalutamide-resistant prostate cancer.
• To determine the role of Stat5a/b in pancreatic ductal adenocarcinoma.
• To investigate the role of Stat5 in sensitizing prostate cancer to radiation.

Worked on T cell antigen receptor (TCR) gene transfer into peripheral mouse CD8+ T-Cells and aimed to dissect different TCR signaling pathways.

• Notch signaling pathway in the carcinogenesis of Pancreatic ductal adenocarcinoma.
• Analysis of dual inhibition of Notch and Jak-stat pathways in Pancreatic cancer.
• To study the role of hedgehog signaling and Notch signaling in cholangiocellular carcinoma.

4. Project titled “Characterization of colonic inflammation and immune cells in the pathogenesis of autoimmune diabetes”.

5. Worked on a project entitled “Polymorphism of eNOS gene”.

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