alexa Yongho Bae | University at Buffalo

Journal of Microbiology and Pathology
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Yongho Bae

Yongho Bae Yongho Bae
Assistant Professor
University at Buffalo
USA
Biography

He Assistant Professor of Pathology and Anatomical Sciences at the University at Buffalo. He received BS in Biotechnology from Ajou University (Korea), MS in Biochemical Engineering from Rutgers University and PhD in Bioengineering from the University of Pittsburgh (Dissertation title: A novel inhibitory pathway linking profilin-1 and breast cancer cell motility). After completing a post-doctoral fellowship at the University of Pennsylvania (Research work: The role of ECM stiffness-mediated mechanosensing on cell cycling), he began his independent academic career at the University at Buffalo. His work has focused on the rapidly growing area of cell the role that mechanical forces play in regulating cellular function. He have been particularly interested in understanding the effect of changing extracellular matrix (ECM) stiffness because many pathological microenvironments, such as those seen in tumors and cardiovascular disease, are stiffer than their physiological counterparts. He have shown that a stiff ECM contributes to pathological behaviors such as increased migration and proliferation. His areas of biomechanical expertise include atomic force microscopy of cells and the use  to model tissue stiffness in vitro.

Research Interest

Vascular Biology and Disease, Mechanobiology, Cell Proliferation, Cytoskeleton and Cell Motility, Atomic Force Microscopy.

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