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Grace Theresa Nicholas Ramena
University of Arkansas
She Grace Ramena,She earned a doctorate degree in molecular biology, microbiology and biochemistry from Southern Illinois University in 2015, a master’s degree in biology from the University of Illinois at Springfield in 2010 and a master’s degree in aquaculture from Acharya Nagarjuna University in Guntur, India in 2002. She worked as a post-doctoral research associate at the Washington University School of Medicine in St. Louis, Missouri. She researched the oligomeric states of ErbB2/ErbB3 receptors and their signal transduction in cell transformation. Before that She worked on research projects at Southern Illinois University’s School of Medicine to determine whether sCLCA2 could induce apoptosis of breast cancer cells but spare normal cells. She later tested potential CLCA2 interactors identified by a yeast two hybrid system. She have discovered how one of them, EVA1, links CLCA2 to epithelial differentiation. She also studied the structural and regulatory requirements for CLCA2 auto proteolysis by developing an in vitro cleavage assay and constructing mutants. Together, her studies helped delineate how human CLCA2 mediates epithelial differentiation and produced insights into CLCA2’s structure and function.
therapeutic molecules,genotoxicity, bacterial infections,cytoxicity