alexa Emerging Techniques in Bioengineering | OMICS International
ISSN: 2155-9538
Journal of Bioengineering & Biomedical Science

Like us on:

Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Emerging Techniques in Bioengineering

Partha Roy*

Department of Bioengineering and Pathology, University of Pittsburgh, USA

*Corresponding Author:
Partha Roy
Department of Bioengineering and Pathology
University of Pittsburgh, USA
Tel: 412-624-7867
Fax: 412-383-8788
E-mail: [email protected]

Received Date: November 28, 2012; Accepted Date: November 28, 2012; Published Date: November 30, 2012

Citation: Roy P (2012) Emerging Techniques in Bioengineering. J Bioeng Biomed Sci S5:e001. doi:10.4172/2155-9538.S5-e001

Copyright: © 2012 Roy P. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Journal of Bioengineering & Biomedical Science

In this special issue titled “Emerging techniques in Bioengineering”, four papers were published. The first paper described a study that examined the potential use of K350, a recently developed 2-aminobenzamide type HDAC (histone deacetylase) inhibitor, in promoting neurite outgrowth. Therapeutic use of HDAC inhibitors has been most extensively studied in the field of cancer. In the last decade, several papers have been published which examined the use of different HDAC inhibitors in the treatment of neurological dysfunctions including epilepsy and Huntington’s disease. In the present study, Marouka et al. reported that treatment of K350 can induce the expression of nur77, an early gene responsible for neuronal differentiation, and promote neurite extension in PC12 cells. Based on these findings, the authors proposed that K350 may be a novel therapeutic agent in the treatment of traumatic brain injury.

In the second paper, Smeal et al. reported a novel technique for capturing dynamics of signal propagation over a large neural network with a high temporal resolution. Specifically, the authors demonstrated the use of targeted path scanning (TPS) for characterizing rapid calcium transients in astrocytes using an ex vivo model. With this technique, the authors were able to show suppression of traveling waves in a model system mimicking epilepsy. This study opens up a possibility of future diagnostic use of TPS for neural and glial pathologies.

In the third paper, Hurley et al. described a novel tissue engineering approach for extracellular matrix remodeling in the context of diabetic cardiomyopathy. Diabetic heart is often associated with increased collagen accumulation (leading to increased stiffness and cardiac dysfunction) and this is thought to be due to attenuated MMP2 expression/activity. In this study, the authors demonstrate that selfassembling peptide nanofiber (NF)-based scaffold provides a superior extracellular environment for MMP2 delivery and matrix remodeling by cardiac fibroblasts isolated from diabetic heart when compared to control matrigel-based ECM substrate. Therefore, peptide NF may have a promising application in cardiac regenerative medicine.

Finally, in the last paper, Brafman provides a comprehensive review of various high throughput screening platforms that are currently being used to study modulation of stem cell behavior by biochemical and biophysical cues from the microenvironment.

Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Recommended Conferences

Article Usage

  • Total views: 11738
  • [From(publication date):
    specialissue-2012 - Jun 24, 2018]
  • Breakdown by view type
  • HTML page views : 7956
  • PDF downloads : 3782
 

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7