alexa Journal of Eye Diseases and Disorders

Journal of Eye Diseases and Disorders
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About the Journal

Journal of Eye Diseases and Disorders is an open access journal that captures the latest research and innovation in the eye care that enable early diagnosis, prevention and cure of the eye diseases and disorders.

Journal of Eye Diseases and Disorders caters to the needs of ophthalmologists, retina specialists, endocrinologists, clinical practitioners, academicians, researchers and students that are keen on the latest developments in this field. The journal encourages manuscript written following the standard research methods as research articles, review articles, case reports, short communication and editorials.

Journal of Eye Diseases and Disorders considers a broad spectrum of topics for publication including but not limited to; visual pathologies, optic nerve damage, retinal damage, Eye diseases, physiology and pathology of vision, visual neuroscience, corneal disorders, neuro-ophthalmology, intraocular pressure, vision loss, ocular diseases, eye cancer, cataract, night blindness, conjunctiva, diabetic retinopathy, visual disabilities, optic nerve, presbyopia, fungal endophthalmitis, glaucoma, phakomatoses, pupil, retina, sclera, vitreous hemorrhage, eye care, vitamin A deficiency etc.

The editorial board comprising of the reputed scholars and practitioners in the eye care industry encourages the authors to make the best use of the open access forum to showcase their scholarly findings for further research in this filed. Authors are requested to submit manuscript at http://www.editorialmanager.com/acrgroup/ or as an e-mail attachment to the Editorial Office at [email protected] / [email protected] / [email protected].

Cataract

Cataract leads to cloudyness in the lens of eyes which causes decrease in eye vision. Due to catarct, light cannot easily pass through retina which causes blurred vision. It often develops slowly. Protein or yellow brown pigment gets deposited in the lens. Cataract is the cause of nearly half of the blindness. It occurs mostly due to aging or sometimes due to trauma or exposure to radiation.

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Glaucoma

Glaucoma is a condition that causes damage to the optic nerve due to build up of fluids in the front part of eye. The extra fluid increases the pressure in the eye damaging the optic nerve. The increased pressure which is known as, intra ocular pressure, if continues to increase, may lead to permanent blindness. It is generally of two types, Open Angle Glaucoma and Angle Closure Glaucoma. It may occur due to: age related mascular degeneration, diabetic retinopathy, retinal detachment.

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Myopia

Myopia, also known as near sigtedness or short sightedness, where distant objects looks blurry and close objects appear normal. It occurs if the cornea is too curved. As a result, light enreing the eye is not focussed correctly and distant objects looks blurred. It may occur due to genetic or environmental factors. The retina in myopic patients is thin. It is the most common eye problem and uncorrected myopia may cause retinal detachment, cataracts and glaucoma.

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Conjunctivitis

Conjunctivitis, also known as Pinkeye, is an inflammation of the cornea. It makes the eye appear red or pink in colur. The most common cause is viral or bacterial and sometimes it may also occur due to exposure to chemicals, irritants and allergies. Tissue that lines back of the eyelid gets inflammed and causes itching, tearing, burning etc.

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Presbyopia

Presbyopia is an eye condition in which the eyes slowly loses the ability to focus quickly on the objects that are near. It is occurs with age when eye lens loses it flexibility beacause of which lens cannot change shape and constricts to focus on close images. With this the eyes gradually loses its ability to focus light directly onto the retina.

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Dry eye

Dry eyes is condition when there is a chronic lack of sufficient lubrication nad moisture on the surface of the eye. Consequences of dry eyes range from subtle but constant eye irritation to significant inflammation and even scarring of the front surface of the eye. symptoms of dry eye includes: Burning sensation, itchy eyes, photophobia, ache, blurred vision.

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Retinal detachment

Retina is a light sensitive membrane located on the back of the eyes. Retinal detachment occurs when retina separates from the back of the eye. It causes loss of vision may be partially or completely. The cells in the retina may be severely deprived of oxygen. There are different types of retinal detachment: rhegmatogenous, tractional, exudative. Causes of retinal detachment may be posterior vitreous detachment, extreme nearsightedness, trauma to eye, being over 50 years old etc.

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Colour blindness

Colour blindness is a condition where there is a difficulty or inability in distinguishing colours. It occurs due to fault in the development if three sets of colour sensing cone cells in the eye. Majority of colour blind people cannot distinguish between green and red. Different shades of colour may look similar. It is more common in men than in women. It is a genetic disorder and women are mostly the carrier and men are most likely to inherit.

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Intraocular Pressure

It is the fluid pressure present inside the eye. By to determining the amount of fluid in the eye the doctor is able to decide if the patient is at a risk of glaucoma. The method used to determine intraocular pressure is Tonometry. The units for the measurement of fluid are Milimeters of Mercury (mmHg).

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Night blindness

Night blindness also known as Nyctalopia ios a type of vision impairment. People with night blindness have poor vision at night or in dimly lit environments. It may occur due to nearsightedness, cataracts, retinitis pigmentosa etc. In rare cases it occurs due to vitamin A deficiency.

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Lazy Eye

Lazy Eye, also known as amblyopia occurs when one eye develops poorly. Vision is weak in that eye and it moves slowly. Using corrective glasses or contact lenses may correct it. It may occur in infants, children and adults.

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Diabetic Retinopathy

Diabetic Retinopathy is a disease of the retina which occurs due to diabetes. It may lead to poor vision and subsequently to complete blindness. The blood vessels in the eye become weak and blood will leak out in the centre of the eye and causes blurry vision.

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Age related Macular Degeneration

It is a physical disturbance in the centre of the retina which is known as macula. It is of two types: Dry macular degeneration and Wet macular degeneration. Causes of age related macular degeneration may be age, smoking, diet, exposure to sunlight, high blood pressure.

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Ophthalmoscopy

It is a test that allows doctors to health of retina, optic disc, vitreous humor. It sis also known as funduscopy to see inside the fundus of the eye.

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Corneal transplant

It is also known as corneal grafting, is a surgery where damaged cornea is replaced by the donor corneal tissue. It is of two types: penetrating keratoplasty, entire cornea is replaced and lamellar keratoplasty, only a part of cornea is replaced.

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Glaucoma Hereditary

Glaucoma is hereditary. Family history increases the risk of glaucoma by four times. Primary open angle glaucoma is the most common glaucoma that is caused hereditarily. It has a genetic link i.e., if a person has the defect in his genes then it causes that individual to be easily affected.

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Molecular Degeneration Amsler Grid

It is a tool that is used by the eye doctors in order to detect vision problems results from damage caused to the optic nerve. The damage is caused by macular degeneration, so the Amsler grid is useful in detecting these problems. Early treatment may help to reduce or slow the vision loss.

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Pigmentary Glaucoma

It is an inherited type of open angle glaucoma. It is mostly seen in men than compared to women. The anatomy of the eye plays an important role in the development of open angle glaucoma. Nearsighted patients are afflicted to this glaucoma. Miotic therapy is a treatment of choice. The drug is in drop form and help to reduce visual blurring in the patients in the young stage. Laser iridotomy is presently investigated in the treatment of this disorder.

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Glaucoma Screening

There are several tests that can help In diagnosis of glaucoma. They are Tonometry, measuring intra ocular pressure, test of optic nerve damage, visual field test, visual acuity and measuring cornea thickness. There are three types of tonometers they are air puff or noncontact tonometer, applanation tonometer and electronic indentation method.

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Congenital Glaucoma

It is present from birth. However it is identified in infancy. It is caused due to improper development of the eye’s aqueous outflow system, thus leading to intraocular pressure, with consequent damage to ocular structures, resulting in loss of vision.

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Glaucoma Medicine

The medication of glaucoma starts with eye drops. The drops must be used exactly as prescribed if not it will damage the optic nerve and thus leads to serious problems. If the doctor prescribes more than one eye drop then some time gap must be maintained between the intake of the eye drops. Because some of the eye drops are absorbed into the blood stream. Some of the commonly used eye drops are Prostaglandins, Beat blockers, Alpha adrenergic agonists and Carbonic anhydrase inhibitors.

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Glaucoma Drugs Research

New classes of drugs are being introduced that act only on the eye’s drainage canal. It is known as trabecular meshwork. It is a main outflow and blockade side of glaucoma. Rho kinase inhibitors target cells in the trabecular meshwork to enhance aqueous humor outflow. It is a clear fluid that maintains the intraocular pressure. In the research works it has shown that it reduces cellular stiffness. ROCK inhibition has the ability to offer neuroprotective and anti-inflammatory effects and also has the ability to enhance blood flow to the optic nerve.

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Advanced Glaucoma Therapeutics

ROCK inhibition has the ability to offer neuro protective and anti-inflammatory effects and also has the ability to enhance blood flow to the optic nerve. An increased understanding of the pathophysiology of glaucoma will lead to the development of new therapeutic agents that intervene and perhaps even reverse glaucomatous damage to the eye.

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Pseudoexfoliation Glaucoma

It is a systemic condition characterized by the deposition of protein like layer on the anterior segment of the eye, most notably on the anterior lens capsule, and other organs. Both genetic and environmental factors play a role in this pathogenesis. It may present unilaterally and bilaterally and it is a main factor for secondary open angle glaucoma.

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Glaucoma Prognosis

It may be treated by medication or surgery or both. The treatment depends upon the type of glaucoma and its severity and even age of the patient. Glaucoma medications help drain excess fluid from the eye and/or decrease the amount of fluid produced. Medications used to treat glaucoma can be administered topically or orally.

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Pediatric Glaucoma

Pediatric glaucoma is hereditary. About 10% of primary congenital/infantile glaucoma cases are inherited. Recent research has identified specific gene mutations linked to this disease; genetic testing and counseling for affected families is available. In the future, there may be genetic therapies available.

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Trauma Related Glaucoma

A blow to the eye, chemical burn, or penetrating injury may all lead to the development of glaucoma, either acute or chronic. Traumatic glaucoma refers to a heterogeneous group of posttraumatic ocular disorders with different underlying mechanisms that lead to the common pathway of abnormal elevation of intraocular pressure (IOP) and increased risk of optic neuropathy.

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Glaucoma Pathophysiology

The main downside or pathology in eye disease is caused by raised pressure level. It's this raised pressure that compresses and damages the second cranial nerve. Once the second cranial nerve is broken, it fails to hold visual data to the brain and this ends up in loss of vision. The raised pressure on the tissue layer causes the cells and nerve neural structures within the sensitive tissue layer to go away and additionally the tiny blood vessels of the tissue layer are compressed depriving it of nutrients.

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Chronic Glaucoma

Chronic eye disease, conjointly referred to as primary glaucoma or POAG, is typically referred to as "the silent malefactor of sight" as a result of within the early stages of the illness there aren't any warning signs — no pain or vision loss or alternative hints that one thing is wrong. as a result of this sneaky nature of the illness and therefore the devastating vision loss it will cause because it progresses, it's essential to own routine eye exams to create certain you're not developing early primary glaucoma.

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Phacolytic Glaucoma

Patients with phacolytic eye disease usually have a history of slow vision loss for months or years before the acute onset of pain, redness, and generally additional decrease in vision. Vision might solely be inaccurate light-weight perception because of the density of the cataract. Symptoms mimic acute acute glaucoma .The history of slow vision loss because of advancing cataract preceding the acute onset of symptoms could be an important clue to the proper designation.

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Natural Remedies for Glaucoma

Use of other drugs continues to extend, though it should be noted that a number of these treatment alternatives haven't any well-tried clinical result. Regular exercise and relaxation techniques are often helpful for lowering eye pressure and will have a positive impact on your overall health and different eye disease risk factors together with high pressure level. Always check with your doctor before beginning any different therapies.

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Glaucoma

It is a group of eye conditions resulting in optic nerve damage, which may cause loss of vision. Abnormally high pressure inside the eye causes this damage. It is the one of the leading causes of blindness. It causes gradual decrease in vision and person becomes blind in the advanced stage. The most common type of Glaucoma is primary open-angle glaucoma. It causes gradual vision loss.

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Glaucoma and Diabetes

The membrane could be a cluster of specialized cells that convert light-weight because it enters although the lens into pictures. The attention nerve or optic tract transmits visual info to the brain. Diabetic retinopathy is one among the vascular complications associated with polygenic disease. This polygenic disease eye drawback is attributable to injury of tiny vessels and is named a "micro vascular complication." Diabetic retinopathy is that the leading reason behind irreversible visual defect in industrialized nations.

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Glaucoma Epidemiology

The worldwide prevalence of glaucoma is increasing. This is due in part to the rapidly aging population. Vision loss from glaucoma greatly impacts the independence of many people who are part of this aging population.

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Diamox Glaucoma

The use of acetazolamide helps to reduce eye pressure; it helps to prevent further eye damage. Medicines are also given to help reduce the pressure in the eyes, commonly as eye drops. Acetazolamide works by blocking the action of an enzyme called carbonic anhydrase. Blocking this enzyme reduces the amount of fluid that you make in the front part of your eye and this helps to lower the pressure within your eye.

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Advances in Glaucoma Diagnosis

The main cause for glaucoma is the increased intraocular pressure. Lowering this pressure will help to reduce the effects of glaucoma. Some of the resources to reduce glaucoma is either use of medication, lasers and surgery. Glaucoma treatment must be continued lifelong but there is no cure for glaucoma.

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Acupuncture for Glaucoma

According to the findings of this trial, auricular acupressure lowers intraocular pressure by around 4 mm Hg for the right eye and around 5 mm Hg for the left eye at four weeks. The safety of acupuncture was not examined in this trial. To date, the ongoing trial "Acupuncture for Glaucoma" has not recruited any participants. On the basis of currently available evidence, the benefit and harm of acupuncture as a therapeutic modality for glaucoma cannot be established. Inclusion of the seven Chinese trials that are awaiting assessment for eligibility in the future may change our conclusions.

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Phacomorphic Glaucoma

It is a term used for secondary open angle closure glaucoma. The increase in thickness of lens from an advanced cataract, a rapidly intumescent lens will lead to pupillary block and angle exposure. Patients with phacomorphic glaucoma complain of acute pain, blurred vision, rainbow-colored halos around lights, nausea, and vomiting.

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Malignant Glaucoma

It refers to sustained ongoing process that is difficult to treat and characteristically progresses to blindness. It is sometimes unresponsive and occasionally worsened with conventional management. The underlying pathology of malignant glaucoma is believed to be aqueous misdirection into or posterior to the vitreous body with anterior displacement of the lens-iris diaphragm.

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Acute Glaucoma

When the pressure inside the eye rises it causes Acute Glaucoma. The symptoms are red eyes, reduced vision and pain in the eye. If not treated it may cause permanent loss of vision. The vision is affected because of the damage to the optic nerve that is present at the back of the eye.

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