Bleeding disorders are a group of disorders that share the inability to form a proper blood clot. Improper clotting can be caused by defects in blood components such as platelets and/or clotting proteins, also called clotting factors. Symptoms of a bleeding disorder include: Bleeding into joints, muscles and soft tissues, Excessive bruising, Prolonged, heavy menstrual periods (menorrhagia) Researchers from Denmark analyzed health data and blood samples of 66,001 people, obtained from two Danish studies that followed participants from 1977 through 2010. The researchers looked for blood type and the presence of two genetic mutations, in addition to occurrence of blood clots and heart attacks.
Type AB blood, they found, was a significant risk factor for blood clots, accounting for 20 percent of the risk for venous thromboembolism. And the risk was especially high when those with AB blood type also had one or both of two genetic mutations, called V Leiden and prothrombin. The researchers also considered incidence of heart attack but found no consistent increased risk.Complete blood count (CBC): to check the amount of blood loss as well as the amount of red and white blood cells you have), platelet aggregation test, bleeding time: to see how fast your blood vessels close to prevent bleeding. Treatment for bleeding disorders varies, depending on the condition and its severity.
For some bleeding disorders, there are clotting factor concentrates that can be infused prophylactically or on-demand at home, to prevent or treat bleeds Many of today's standards of research are based upon what was learned from clinical trials in the past such as reducing complications of clots, what causes clots. Some bleeding disorders, such as hemophilia, can be inherited or acquired. Others can occur from such conditions as anemia, cirrhosis of the liver, HIV, leukemia and vitamin K deficiency, lot of research is being done on these topics.