Meniere’s disease is a condition in which there is an excess of fluid in the inner ear. The excess fluid disturbs the ear’s balance and hearing mechanisms and produces a range of symptoms: vertigo (a form of dizziness where your surroundings appear to spin) tinnitus (an abnormal ringing noise inside the ear) fluctuating hearing loss a feeling of pressure or fullness in the ear due to fluid build-up.
During the acute attack the excessive endolymphatic fluid pressure causes distension and rupture of Reissner's membrane. This results in the release of potassium-rich endolymph into the perilymphatic space and causes injury to the sensory and neural elements of the inner ear. Between attacks, Reissner's membrane may reattach itself, the chemical balance is restored, and symptoms remit.
Of the total of 306 patients treated for Meniere's disease in the target hospitals, 131 (43 %) could be identified in a careful re-evaluation as really having had this disease according to the latest AAO-HNS criteria. The last class (Improbable/other disease) also includes 4 cases that turned out to be falsely coded, without any document referring to Meniere's disease.
Medications can be used during an attack to reduce the vertigo, nausea/vomiting or both. Some drugs used for this include diazepam (Valium), lorazepam (Ativan), promethazine (Phenergan), dimenhydrinate (Dramamine Original Formula), and meclizine hydrochloride (Antivert, Dramamine Less Drowsy Formula).
Major research on disease:
High incidence of Meniere-like symptoms in relatives of Meniere patients in the areas of Oulu University Hospital and Kainuu Central Hospital in Finland.Correspondingly, of course, there may have been a few cases of Meniere's disease that had been falsely assigned some other diagnosis code.some researchers are questioning this theory because membrane ruptures were found post mortem in temporal bones.