Multiple myeloma also known as plasma cell myeloma or Kahler's disease .It is a cancer of plasma cells, a type of white blood cell normally responsible for producing antibodies. In multiple myeloma, collections of abnormal plasma cells accumulate in the bone marrow, where they interfere with the production of normal blood cells. Bisphosphonate treatment is often started along with chemo. If the areas of damaged bone continue to cause symptoms, radiation therapy may be used.
The probability or risk of individuals getting/dying from the disease during a specified period is also called cumulative risk. For cancer, it is expressed as the number of new born children (out of 100) who would be expected to develop/die from a particular cancer before the age of 75 if they had the rates of cancer incidence/mortality observed in the period in the absence of competing causes of death.