Non-Hodgkin lymphomas (NHLs), also known as non-Hodgkin disease are diverse group of blood cancers that include any kind of lymphoma except Hodgkin's lymphomas. Types of NHL vary significantly in their severity, from slow growing to very aggressive types.Lymphomas are types of cancer derived from lymphocytes, a type of white blood cell. In Sweden, Denmark, and Finland, the NHL incidence increased in both genders and all age categories by about 4% every year up until the early 1990s. Time trends of NHL were not reciprocated and explained by trends for other lymphoproliferative malignancies nor explained by trends in NHL as secondary primaries or NHL diagnosed postmortem.
The form of treatment chosen depends on the type of lymphoma and the stage of disease, as well as other factors including age, prior therapies received and the patient's overall health.
Before starting treatment, patients should discuss all available treatment options with their physician.Some patients may relapse (disease returns after treatment) or become refractory (disease does not respond to treatment). Other tests that may be helpful in evaluating suspected NHL include the following:
• Immunophenotypic analysis of lymph node, bone marrow, peripheral blood
• Cytogenetic studies: NHL occasionally associated with monoclonal gammopathy; possible positive Coombs test; maybe hypogammaglobulinemia