Breast cancer is the most common cancer in women worldwide. Cancer starts when cells begin to grow out of control. Cells in nearly any part of the body can become cancer, and can spread to other areas of the body. Breast cancer is a malignant tumor that starts in the cells of the breast. A malignant tumor is a group of cancer cells that can grow into surrounding tissues or spread to distant areas of the body. The disease occurs almost entirely in women when compare to men.
Statistics of Pagets Disease of the Breast in Finland: The annual incidence in Finland in 2011 was 4869. In Finland, the predicted breast cancer-specific five-year survival rate for patients under follow up from 2007 to 2009 is 89%. The incidence is increasing and more than 5100 new breast cancers are estimated to be found in the year 2020.
The aim of surgical treatment is to remove the breast tumour and metastatic axillary lymph nodes, thus preventing LRRs and improving survival. Surgery enables pathological assessment and staging of the tumour, providing important knowledge regarding prognosis and tailoring of adjuvant treatments. Moreover, the accuracy of axillary nodal staging is dependent on the number of examined lymph nodes, that is, on the quality of surgery and pathological assessment.