alexa Journal of Formulation Science and Bioavailability

Journal of Formulation Science & Bioavailability
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About the Journal

Journal of Formulation Science & Bioavailability is a peer reviewed journal that offers the latest research advancements on Formulation Sciences by including topics like applied analytical and bioanalytical sciences, chromatography, biomedical & pharmaceutical analysis, clinical therapeutics to various toxicology measures, pharmaceutics, biopharmaceutics, pharmacokinetics, pharmaceutical chemistry, pharmacodynamics, drug delivery, biotechnology, pro-drugs, physical chemistry, chemical stability, dosage form design, medicinal chemistry, pharmacology, drug absorption and metabolism, pharmacokinetics and pharmacodynamics, pharmaceutical and biomedical analysis, drug delivery (including gene delivery), drug targeting, pharmaceutical technology, pharmaceutical biotechnology and clinical drug evaluation.
The Journal also includes research on various topics related to Bioavailability, including Pharmacokinetics, Biopharmaceutics, Bioequivalence, Bioequivalence and simulation, Biosimilars requirement, Biowaivers, Bioavailability enhancement, Drug delivery systems Drug delivery pathway, Biosimilars oncology, Biosimilars – regulatory affairs, Biosimilars and pharmacology, Drug development systems, Bioavailability, Biosimilars models, General Bioequivalence and Bioavailability metrics
The Journal accepts original manuscripts in the form of research article, review article, short communication, case report, letter-to-the-Editor and Editorials for publication. All the published articles are open access and can be accessed online without any subscription charges. The journal extensively enhances the worldwide visibility of the scholars that contribute their research work.
The Editorial Manager System helps in maintaining the quality of the peer review process and enables the authors to track the review and publication process in an automated way. Experts in the field of Cell Science and Apoptosis take up the review process under the guidance of Editor-in-Chief. . Approval of at least two independent reviewers and the editor is mandatory for the acceptance of the manuscript for publication.

Biosimilar

Biosimilar drugs are biopharmaceutical drug ,specially designed to have similar active properties that has previously been licensed.These are mostly used to treat autoimmune diseases like Rhumatic orthrites for example: Genotropin , Herceptin etc.Mostly the simsialr Properties would be same size, therapeutic action, soluability, shape , category etc.
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Journal of Clinical Pharmacokinetics ; Journal of Therapeutic Advances in Drug Safety; Journal of Investigational New Drugs; Journal of Pharmaceutical Research; Journal of Drugs ; Drug Metabolism Reviews.

Clinical Pharmacokinetics

Clinical Pharmacokinetics can be definied as, it is a study of drug disposition in the human body, which is an integral part of drug development and rational use.In this Clinical pharmacokinetics even distribution of drug and efficacy of the drug can be estimated.
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Journal of Clinical Pharmacokinetics ; Journal of Therapeutic Advances in Drug Safety; Journal of Investigational New Drugs; Journal of Pharmaceutical Research; Journal of Drugs ; Drug Metabolism Reviews

BCS Classification

Biopharmaceutics Classification System is a classification of drugs depending on their permeability and Solubility to improve the efficiency of drug development and strategy for identifying expendable clinical bioequivalence tests.Thare are four categories of drugs in which class 1 drugs, class 2 drugs ,class 3 drugs, and class 4 drugs.
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Journal of Therapeutic Advances in Drug Safety; Journal of Investigational New Drugs; Journal of Pharmaceutical Research; Journal of Drugs ; Drug Metabolism Reviews; Journal of Pharmacology and Therapeutics.

Pharmaceutical Bioavailability

The Bioavailability can be defined as extent and rate at which the drug enters systemic circulation there by able to have an active effect. Bioavailability can be calcualted use Absolute Bioavailability and Relative Bioavailability. Many Factors effect the bioavailability such as pH, particle size, permeability, solubility etc 
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Pharmaceutical Pharmacokinetics

Pharmaceutical Pharmacokinetics branch of science which deals with the movement of the drug in the body or how an organism affects a drug and it explains the Movementof the drug in the body. In this Pharmacokinetics process it involves the absorption, distribution, Metabolism and Elimination. 
Related journals
Journal of Clinical Pharmacokinetics ; Journal of Therapeutic Advances in Drug Safety; Journal of Investigational New Drugs; Journal of Pharmaceutical Research; Journal of Drugs ; Drug Metabolism Reviews

Pharmaceutical Pharmacodynamics

Pharmaceutical Pharmacodynamics is a branch of science which deals with how a drug effect an organism and their mechanism or simply what drug does to the body. In this process the mechanism of action of the drug on specific site and its reaction, simply the efficacy of the drug involves.
Related Journals
Journal of Pharmacology and Therapeutics; Journal of Clinical Pharmacokinetics ; Journal of Therapeutic Advances in Drug Safety; Journal of Investigational New Drugs; Journal of Pharmaceutical Research

Bioequivalent

The two products are said to be bioequivalent if they are only pharmaceutically equivalent and their rate and extent of availability after administration in the same molar dose are similar and it can also be defined as absence of a greater-than-allowable difference between the systemic bioavailability of a test product and that of a reference product.
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Pharmaceutical Analysis

Pharmaceutical Analysis is a Branch of Pharmacy which involves Series of Process of drug identification, determination, quantification and purification of the substance.Analysis of drug involves the purity of the drug, particle size , standard of the drug.instuments used in analysis are HPLC, chromatography, FTIR etc.
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Journal of Clinical Pharmacokinetics ; Journal of Therapeutic Advances in Drug Safety; Journal of Investigational New Drugs; Journal of Pharmaceutical Research; Journal of Drugs ; Drug Metabolism Reviews.

Novel drug delivery

Novel drug delivery system is the advanced technique by which a drug is delivered can have a significant effect on its efficacy.This is the advanced Technique in which involes the delivering the drug only to the site of action, and showing good therapeutic action.
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Regualtary affairs

Regulatory affairs is a new profession in which governaments developed to protect public health by controlling the safety and efficacy of the products in the areas including pharmaceuticals, veterinary medicines, medical devices, pesticides, agrochemicals, cosmetics and complementary medicines
Related Journals
Journal of Pharmacology and Therapeutics; Journal of Clinical Pharmacokinetics ; Journal of Therapeutic Advances in Drug Safety; Journal of Investigational New Drugs; Journal of Pharmaceutical Research

Biowavier

The Biowaiver is applied to a regulatory drug approval process where the efficacy and safety part of the dossier (application) is approved based on evidence of equivalence other than through in vivo equivalence testing.Comparison of test and reference,They do not apply to food effect bioavailability studies or other pharmacokinetic studies.
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Journal of Clinical Pharmacokinetics ; Journal of Therapeutic Advances in Drug Safety; Journal of Investigational New Drugs; Journal of Pharmaceutical Research; Journal of Drugs ; Drug Metabolism Reviews.

Liposome

A Liposome is a spherical vesicle having at least one lipid bilayer. The liposome can be used as a vehicle for administration of nutrients and pharmaceutical drugs.liposome contains phospholipid molecules enclosing a water droplet, these are mostly used to carry the drugs to the site of action.
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Therapeutic equivalence

The active moieties of the drug said to be Therapeutic equivalents only if they are pharmaceutical equivalents and if they have same clinical effect and safety profile. By this therapeutic equivalence the efficacy of drug can be detected and adverse reactions of the drug can be estimated.
Related Journals
Journal of Clinical Pharmacokinetics ; Journal of Therapeutic Advances in Drug Safety; Journal of Investigational New Drugs; Journal of Pharmaceutical Research; Journal of Drugs ; Drug Metabolism Reviews

Relative bioavailability

The Bioavailability can be calculated using Relative bioavilability a generic formulation is compared with a standard formulation of same of same drug in same dosage form. In this Area under curve can be calculated.The generic drug is related to the another drug.

Related Journals
Journal of Pharmacology and Therapeutics; Journal of Clinical Pharmacokinetics ; Journal of Therapeutic Advances in Drug Safety; Journal of Investigational New Drugs; Journal of Pharmaceutical Research

Absolute bioavailability

Absolute bioavailability can be defined as the amount of drug from a formulation that reaches the systemic circulation relative to an intravenous (IV) dose.The area under can be calculated , It is the fraction of the drug absorbed through non-intravenous administration compared with the corresponding intravenous administration of the same drug.
Related Journals
Journal of Therapeutic Advances in Drug Safety; Journal of Investigational New Drugs; Journal of Pharmaceutical Research; Journal of Drugs ; Drug Metabolism Reviews; Journal of Pharmacology and Therapeutics

Dissolution

Dissolution is the process by which a substance forms a solution in a solvent. In which drug diffuses into the solvent and forms into a solution.

Fludised Bed dryer

A fluid bed dryer is a kind of equipment which can be used for applications like drying of powders, mixing of powders and agglomeration. This is efficiently employed for applications in chemical, pharmaceutical, dyetuff, foodstuff, dairy and various other process industries. Fluid bed dryers are often employed with the spray dryers and granulation systems for effective drying, mixing, granualtion, finishing and cooling of powdered substances. These are often preferred over rotary dryers for drying and cooling a wide range of polymer materials which require precise control of residence time and temperature for effective processing.Fluid bed dryer works on a principle of fluidization of the materials. In fluidization process, hot air or gas flow is introduced through the bed of solid particulates. This gas or air will move upwards through the spaces between the particles. As the velocity increases, upward drag forces on the particles increase and at a stage become equal to the gravitational forces beneath. Hence the bed is said to be fluidized and the particles are suspended in the fluid.

Drug Contraindications

Drug Contraindications denotes that alert ought to be utilized when two medications or methodology are utilized together.

HPLC Technique

High-performance liquid chromatography (HPLC) formerly referred to as high-pressure liquid chromatography), is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material. Each component in the sample interacts slightly differently with the adsorbent material, causing different flow rates for the different components and leading to the separation of the components as they flow out the column.

Oral bioavailability

Oral bioavailability (F%) is the fraction of an oral administered drug that reaches systemic circulation. After intravenous administration, a drug is directly and fully available in the bloodstream and can be distributed via systemic circulation to the point where a pharmacological effect takes place. If a drug is administered orally, it has to cross further barriers to reach the systemic circulation, which can significantly reduce the final extent of a drug in the bloodstream.

Clinical Pharmacology Science

Clinical pharmacology is the science of drugs and their clinical use. It is underpinned by the basic science of pharmacology, with added focus on the application of pharmacological principles and quantitative methods in the real world. It has a broad scope, from the discovery of new target molecules, to the effects of drug usage in whole populations.

Drug Disposition

Drug disposition is an general term for the absorption, distribution, metabolism, and excretion of a drug that has been administered.

Side Effect

Side effect is usually regarded as an undesirable secondary effect which occurs in addition to the desired therapeutic effect of a drug or medication. Side effects may vary for each individual depending on the person's disease state, age, weight, gender, ethnicity and general health.

AUC

The area under the plasma drug concentration-time curve (AUC) reflects the actual body exposure to drug after administration of a dose of the drug and is expressed in mg*h/L. This area under the curve is dependant on the rate of elimination of the drug from the body and the dose administered.

Passive Transport

Passive transport is a movement of ions and other atomic or molecular substances across cell membranes without need of energy input. Unlike active transport, it does not require an input of cellular energy because it is instead driven by the tendency of the system to grow in entropy. The rate of passive transport depends on the permeability of the cell membrane, which, in turn, depends on the organization and characteristics of the membrane lipids and proteins.


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