Carrion's disease is an infection by Bartonella bacilliformis which is transmitted through sand-fly bites, especially Lutzomia verrucarum. It is endemic to the Andes Mountains of South America, especially in Peru, at 500 to 3000 meters above the sea level. Symptoms are fever, anorexia, malaise, nausea and/or vomiting. Research in this area has been limited and diagnostic and treatment guidelines are based on very low evidence reports. Carrion’s disease incidence is not found in France.
Statistical analysis of Carrion's disease shows that it is complicated by superinfections in 35% of cases. [Source: http://aac.asm.org/content/48/6/1921.full]
The drug of choice during the acute phase is Quinolones such as ciprofloxacin or Chloramphenicol in adults and Chloramphenicol plus beta lactams in children. For the chronic phase, Rifampin or macrolides are used to treat both adults and children.
Recent investigations show that Candidatus Bartonella ancashi may cause verruga peruana, although it may not meet all of Koch's postulates. Carrion's disease is found only in Peru, Ecuador, and Colombia. It is endemic in some areas of Peru.