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Malignant Peripheral Nerve Sheath Tumors

  • Malignant peripheral nerve sheath tumors

     Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas on peripheral nerves or nerve sheath. These MPNSTs can occur on any cell type and differs from one to other. A sarcoma is regarded as MPNST only when it is raised on the peripheral nerve or it exists on neurofibroma. MPNSTs usually present as an enlarging palpable mass. Pain is a variable complaint. 

  • Malignant peripheral nerve sheath tumors

      Rapid enlargement occurs more often in the setting of NF1 and should raise concern for malignant degeneration of a neurofibroma. In France The prevalence of malignant peripheral nerve sheath tumor (MPNST) among the general population is only 0.001%.

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