The Heymann model of experimental membranous nephropathy in rats, which closely the human disease, suggests that the highly specialized and terminally differentiated glomerular epithelial cell or podocyte is the target of injury.
1-10 per 100,000 person-years. Prevalence: 20-70 per 100,000. Strongest risk factor: women 2-3x higher incidence and prevalence rates. In approximately 25% of cases the disease is secondary, being greater the percentage in children and elderly patients.
The six month treatment involves alternate months of (into a vein initially and then by mouth) and tablets (a powerful ). You will also receive tablets to protect you from some of the possible side effects. You will collect your treatment once a month from the CAPD Unit on Albert Ward and be seen monthly in the outpatients clinic, with regular
An international team of researchers from France, Germany, and the US have identified a protein that turns a person's against itself in a form of kidney disease called membranous nephropathy (MN). The new research was presented at ASN Kidney Week 2014 in Philadelphia and published online in the New England Journal of Medicine.