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Septic Arthritis

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  • Septic Arthritis

    Septic Arthritis is also known as infectious arthritis, bacterial, or fungal arthritis. It is the purulent invasion of a joint by an infectious agent which produces arthritis. The condition is an inflammation of a joint that's caused by infection. Typically, septic arthritis affects one large joint in the body, such as the knee or hip. Less frequently, septic arthritis can affect multiple joints. Septic arthritis is considered a medical emergency. If untreated, it may destroy the joint in a period of days. The infection may also spread to other parts of the body.

  • Septic Arthritis

    Pathophysiology: The major consequence of bacterial invasion is damage to articular cartilage. This may be due to the particular organism's pathologic properties, such as the chondrocyte proteases of S aureus, as well as to the host's polymorphonuclear leukocytes response. The cells stimulate synthesis of cytokines and other inflammatory products, resulting in the hydrolysis of essential collagen and proteoglycans. Infection with N gonorrhoeae induces a relatively mild influx of white blood cells (WBCs) into the joint, explaining, in part, the minimal joint destruction observed with infection with this organism relative to destruction associated with S aureus infection.

  • Septic Arthritis

    Statistics: Septic arthritis is a serious condition in any part of the world. The potential for major complications makes its diagnosis and early treatment an emergency. There is no doubt that the major factor in the improved management of septic arthritis in the last century was the discovery of antibiotics. In 1920 the mortality for a child with septic arthritis was around 10%, and this was reduced to less than 1% by 1970 [33]. There have been no prospective studies looking specifically for prognostic factors in septic arthritis; nevertheless, certain factors have regularly been associated with poor outcome.

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