Pathophysiology: Hepatitis refers to an inflammatory disease which is fairly common and mainly affects the liver. Viral hepatitis is classified as A, B, C, D, E and G. All types of hepatitis viruses cause similar kind of liver damage. Inflammation happens throughout whole liver and hepatocytes are destroyed by cytotoxic cytokines and natural killer cells being part of inflammatory process. Cellular necrosis takes place but liver usually able to repair itself and regain complete function if no other complications occur.
Disease Statistics: Hepatitis A is preventable by vaccines in France. People coming back from high endemic countries usually show its symptoms. In France viral hepatitis E cases are more likely autochthonous than imported. In France, more than 500,000 individuals are living with chronic hepatitis B or C, with 4000 deaths attributable to this hepatitis.
Treatment: Intravenous rehydration is given as supportive care but no specific emergency treatment is recommended as such. Patients are admitted in conditions of severe complications. Evaluation for hepatic encephalopathy is done. Certain patients may benefit from pharmacologic therapy. Patients are advised to avoid prolonged or vigorous physical exertion until their symptoms improve and maintain adequate hydration.
Research: The study was presented by Institut de veille sanitaire which is among the primary centres of hepatitis studies in the France.