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Haematology Scholarly Peer-review Journal

Diabetes was induced in CD1 mice by Streptozotocin (STZ), as described previously. STZ (Sigma-Aldrich) was dissolved in 50 mM sodium citrate buffer (pH 4.5) and a final concentration of 6 mg/ ml was made. The animals were injected intraperitoneally at a dose of 45 mg/kg/day. Treatment was repeated for 5 consecutive days. Blood glucose level was measured, in non fasted animals on alternate days and mice were considered diabetic when blood glucose levels exceeded 250 mg/dL. Serum biochemical variables like CHO and TGY had significant effect with increase in db/db mice on the other hand there were significant decrease in CHO and TGY in STZ induced CD1 mice. The liver enzymes AST and ALT showed significant decrease in STZ induced CD1 mice as reported previously on other species after overnight fasting but there were no significant changes in db/db mice. Scholarly peer review is the process of subjecting an author'sscholarlywork, research, or ideas to the scrutiny of others who are experts in the same field, before a paper describing this work is published in a journal. The work may be accepted, considered acceptable with revisions, or rejected. Peer review requires a community of experts in a given (narrowly defined) field, who are qualified and able to perform reasonably impartial review.
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Last date updated on October, 2020