|Lupus nephritis (LN) is staged according to the classification revised by the International Society of Nephrology (ISN) and the Renal Pathology Society (RPS) in 2003. Another factor that has been described to contribute to the poor prognosis of lupus nephritis is the antiphospholipidsyndrome (APS). APS in patients with systemic lupus erythematosis (SLE) can occur in addition to or independent of LN. A kidney biopsy was performed and 6 glomeruli were examined on light microscopy. One glomerulus was completely sclerotic and the remaining five showed a slight increase in mesangial matrix on trichrome staining and diffuse basement membrane thickening with on silver staining.
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