Carrion's disease is an infectious disease produced by Bartonella bacilliformis. The clinical symptoms of bartonellosis are pleomorphic and some patients from endemic areas may be asymptomatic. The two classical clinical presentations are the acute phase and the chronic phase, corresponding to the two different host cell types invaded by the bacterium (red blood cells and endothelial cells).
Statistical analysis of Carrion's disease shows that the male to female ratio is 3: 2 in Germany. More than 70% of Bartonella endocarditis cases have occured in men. [Source: https://books.google.co.in/books? id=whb9hsUgZtwC&pg=PA505&lpg=PA505&dq=incidence+ of+Carri%C3%B3n%E2%80%99s+disease+in+Germany&source= bl&ots=CfhY_lNDvO&sig=mTA9U0HpBEAxTH3bChi_TSoEqyo& hl=en&sa=X&ved=0ahUKEwiXgLrBmvzKAhWEGY4KHVV 5BvMQ6AEIPjAF#v=onepage&q=incidence%20of%20Carri%C3%B3n%E2%80% 99s%20disease%20in%20Germany&f=false]
The drug of choice during the acute phase is Quinolones such as ciprofloxacin or Chloramphenicol in adults and Chloramphenicol plus beta lactams in children. For the chronic phase, Rifampin or macrolides are used to treat both adults and children.
Recent investigations show that Candidatus Bartonella ancashi may cause verruga peruana, although it may not meet all of Koch's postulates. Carrion's disease is found only in Peru, Ecuador, and Colombia. It is endemic in some areas of Peru.