Non-melanoma skin cancer(NMSC) is a malignant tumor that starts in cells of the skin. Malignant means that it can spread, or metastasize, to other parts of the body. Non melanoma skin cancer includes 2 main types: basal cell skin cancer and squamous cell skin cancer. NMSC incidence was 119/100,000 for women and 145/100,000 for men in the most recent screening period in Schleswig-Holstein (2008–2010). During implementation of SCREEN (2003–2004), incidence increased from 81.5/100,000 to 111.5/100,000 (1998–2000) by 47% for women and 34% for men. All age groups in women were affected by the increase, but increases for men were mostly limited to the older age groups. Incidence in Saarland first increased slowly, but increased steeply with the introduction of the nation-wide skin cancer screening in 2008
To make scientific advances, doctors create research studies involving volunteers, called clinical trials.Sometimes people have concerns that, in a clinical trial, they may receive no treatment by being given a placebo or a “sugar pill.” However, placebos are usually combined with standard treatment in most cancer clinical trials. When a placebo is used in a study, it is done with the full knowledge of the participants. Treatment for non-melanoma skin cancer is completely successful in approximately 90% of cases. Photodynamic therapy, Medicines put on the skin, such as topical fluorouracil (5-FU) and topical imiquimod, Laser surgery.