Entamoeba coli, E. hartmanni, E. polecki, Endolimax nana, and Iodamoeba buetschlii are generally considered nonpathogenic. They are found only in the lumen (cavity) of the intestinal tract. A total of 491 fecal samples collected from residents of an area with a high incidence of amebic liver abscess (ALA) ,were subjected to PCR analysis. Outcome was compared with the results of microscopy and antiamebic antibody status .Prevalence of E. histolytica and E. dispar was found to be 9.2% (45 of 491) based on microscopy versus 14.3% (70 of 491) according to the results of PCR (P = 0.02).
The key to diagnosis and treatment of disease is knowledge of the epidemiologic risk factors and clinical manifestations, a rational approach to diagnosis, and an understanding of the sites of action and uses of anti-amebic drugs. This knowledge of treatment provides a context for consideration of intestinal infection with less common protozoan pathogens such as Dientamoeba fragilis and Balantidium coli and 'nonpathogenic' protozoa such as Blastocystis hominis and Entamoeba coli. Good sanitary practice, as well as responsible sewage disposal or treatment, are necessary for the prevention of E.histolytica infection on an endemic level. E.histolytica cysts are usually resistant to chlorination, therefore sedimentation and filtration of water supplies are necessary to reduce the incidence of infection