Parkinson’s disease is a degenerative disorder of the motor system in the central nervous system. It is caused due to the death of the dopamine generating cells of the mid brain. Parkinson’s disease is considered a synucleiopathy due to an abnormal accumulation of alpha-syncline protein in the brain in the form of Lewy bodies, as opposed to other diseases such as Alzheimer's disease where the brain accumulates tau protein in the form of neurofibrillary tangles.
Symptoms Symptoms of Parkinson's disease differ from person to person. Parkinson’s disease affects the nerve cells in the brain that produce dopamine. Parkinson’s disease symptoms include muscle rigidity, tremors, and changes in speech and gait. After diagnosis, treatments can help relieve symptoms, but there is no cure.
In Germany, epidemiological information on Parkinson‟s Disease (PD) is rare. The only study for Germany, however, showed a lower prevalence compared to calculations with a crude prevalence of 713 (≥65 years). Turning to the age-specific prevalences, estimated 96 cases at ages 50-54, which increased exponentially up to age 85-89. In comparison to the 361 cases in age group 60-64, the prevalence had nearly doubled in age group 65-69 (671 cases) and increased nine-fold for those aged 85- 89 (3,378 cases).