Rat-bite Fever | Germany| PDF | PPT| Case Reports | Symptoms | Treatment

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Rat-bite Fever

  • Rat-bite Fever
    Rat-bite fever (RBF) is an infectious disease caused by two different bacteria. Streptobacillary RBF is caused by Streptobacillus moniliformis in North America while spirillary RBF or sodoku is caused by Spirillum minus and occurs mostly in Asia. Disease has been reported in mice, birds, guinea pigs, and nonhuman primates. The majority of cases are due to the animal's bite. Symptoms depend on the bacteria that caused the infection and include recurrent fever, myalgia and rash. Symptoms usually occur 3-10 days after exposure to an infected rodent, but can be delayed as long as 3 weeks.
  • Rat-bite Fever

    People who keep rats as pets, laboratory technicians and pet shop employees working with rats, are at increased risk of the disease. The exact incidence of the disease is not clearly known. Rat-bite fever can be treated readily with antibiotics, but untreated S. moniliformis infections are estimated to be fatal. It may cause complications like infection of the brain or soft tissue, infection of the heart valves, inflammation of the salivary glands, the tendons and the heart lining. People that handle rats or clean their cages should wear protective gloves, wash their hands after contact.

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