Thrombocytopenia is defined as a platelet count below 150*109/l, caused by accelerated platelet destruction or decreased production. It is classified as mild with a platelet count of 100-150*109/l, moderate at 50-100*109/l and severe with less than 50*109/l. Thrombocytopenia is secondly to anaemia as the most common hematologic abnormality during pregnancy. Indeed, a platelet count <150*109/l can be observed in 6 to 15% of pregnant women at the end of pregnancy. Thrombocytopenia is usually moderate (<100*109/l in only 1% of women) and often incidentally detected on routine blood count. Gestational Thrombocytopenia (GT) is considered the most prevalent cause of thrombocytopenia during pregnancy accounting for about 75% of cases. The etiology is unknown, but it is considered to be due to the relative hemodilution of pregnancy, amplified by the capture or destruction of platelets in the placenta.
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Last date updated on September, 2014