Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a common malignant disease worldwide. Partial hepatectomy remains the best hope for a cure but is suitable for only 9% to 27% of patients . The presence of severe liver cirrhosis often precludes hepatectomy in patients with HCC due to high hepatic failure rate after operation. In the past decade, image-guided thermal ablation as a minimally invasive technique has been widely used for the treatment of small HCC in patients who have high surgical risks .With improvements in devices and techniques, radiofrequency ablation (RFA) and microwave coagulation therapy (MWCT) have displayed potential capability for treating HCC measuring larger than 3 cm . However, the complete ablation rate can reach only 89%~98.6% using thermal ablation. Moreover, increased risk of tumor seeding after percutaneous thermal ablation for HCC remains . Theoretically, surgical resection of the tumor after thermal ablation will take advantage of reducing the risk of tumor residual without increasing the risk of hepatic failure. Recently, laparoscopic resection of liver tumors has been developed and could reduce morbidity . With the laparoscopic approach several advantages can be obtained: early mobilisation and feeding, decreased postoperative pain, reduction of respiratory complication, shorter hospital stay, earlier commencement of adjuvant therapy . Moreover, a lesser destruction of abdominal wall porto-systemic shunts may reduce the increase of portal hypertension and consequent postoperative bleeding. microwave coagulation therapy combined with laparoscopic liver resection for hepatocellular carcinoma in cirrhotic patients is feasibl and safe. Since the number of patients in our study is limited, further prospective evaluations are required to assess the long term results of this procedure. OMICS Group International is one of the leading Open Access Publishing houses, which has around 700+ peer-reviewed journals, 50,000+ editorial board members, and highly qualified, expert reviewers to meet the objectives of the Peer-Review Process. OMICS Group International peer-review policies are highly appreciated, accepted and adaptable to the criteria that have been prescribed by the international agencies such as NIH, PubMed etc. OMICS Group International also organizes 3000+ International Scientific Conferences per year globally.

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Last date updated on April, 2024