Amniotic fluid embolism (AFE) is a pregnancy complication that causes life-threatening conditions, such as heart failure. It can affect you, your baby, or both of you.Amniotic fluid embolism is caused by fetal antigens in the amniotic fluid stimulating a cascade of endogenous immune mediators, producing a reaction similar to anaphylaxis.
Biochemical mediators found in the amniotic fluid are thought to trigger the main features of anaphylactic reaction with multisystem involvement.The disorder ordinarily happens amid work, not long after vaginal or cesarean conveyance, or amid second-trimester widening and clearing strategies. In the national registry, 70% of the cases happened amid work, 19% were recorded amid cesarean conveyance, and 11% happened after vaginal delivery. All of the cases noted amid cesarean area had their onset not long after conveyance of the newborn child.
The overall maternal mortality rate in India during 2007- 2009 was 212 per 100,000 live births1 . 50-98% of maternal deaths in this country are caused by direct obstetric causes viz. haemorrhage, infection, and hypertensive disorders, ruptured uterus, hepatitis, and anemia.