Avascular necrosis is the death of bone tissue due to a lack of blood supply. Also called osteonecrosis, avascular necrosis can lead to tiny breaks in the bone and the bone's eventual collapse. The blood flow to a section of bone can be interrupted if the bone is fractured or the joint becomes dislocated.Avascular necrosis typically causes no symptoms; however, as the disease progresses it becomes painful.
At first, you may experience pain when you put pressure on the affected bone. Then, pain may become more constant. If the disease progresses and the bone and surrounding joint collapse, you may experience severe pain that interferes with your ability to use your joint. The time between the first symptoms and collapse of the bone may range from several months to more than a year. If avascular necrosis is caught early, treatment may involve taking medications to relieve pain or limiting the use of the affected area.
If your hip, knee, or ankle is affected, crutches may be necessary to take weight off the damaged joint. Your doctor may also recommend range of motion exercises to help keep the affected joint mobile. It is also associated with Osteoarthritis and Knee injuries. The incidence of hand, hip and knee OA increases with age, and women have higher rates than men, especially after the age of 50 years.
A levelling off or decline occurs at all joint sites around the age of 80 years. The age- and sex-standardized incidence rate from the Fallon Community Health Plan in Massachusetts (USA) was highest for knee OA 240/100,000 person-years, with intermediate rates for hand OA (100/100,000 person-years) and lowest observed rates for hip OA (88/100,000 person-years). Incidence rates found by the Dutch Institute for Public Health (RIVM) in 2000 were of a similar level. According to a statistical analysis there are Extrapolated Incidence of Avascular Necrosis is 39157 in India.