Botulism is an uncommon and conceivably lethal sickness brought on by a poison created by the bacterium Clostridium botulinum. The illness starts with shortcoming, inconvenience seeing, feeling tired, and inconvenience talking. This may then be trailed by shortcoming of the arms, mid-section muscles, and legs. The ailment does not as a rule influence cognizance or cause a fever.Botulism can happen in a couple of distinctive ways. The bacterial spores that cause it are basic in both soil and water.
The muscle shortcoming of botulism distinctively begins in the muscles supplied by the cranial nerves. A gathering of twelve nerves controls eye developments, the facial muscles and the muscles controlling biting and gulping. Twofold vision, hanging of both eyelids, loss of outward appearance and gulping issues might along these lines happen.
To investigate suspected cases of Botulism outbreaks in India, as no ELISA kits were available, resorted to mouse neutralization test and molecular tests such as PCR7. However, botulinum antitoxin required to do neutralization tests in mice is not easily available and a large number of mice will be required to do this test. As these tests are not routine diagnostic tests, cost involved and formalities required to indent mice delays the results.