Parkinson’s disease is a degenerative disorder of the motor system in the central nervous system. It is caused due to the death of the dopamine generating cells of the mid brain. Parkinson’s disease is considered a synucleiopathy due to an abnormal accumulation of alpha-syncline protein in the brain in the form of Lewy bodies, as opposed to other diseases such as Alzheimer's disease where the brain accumulates tau protein in the form of neurofibrillary tangles.
Symptoms Symptoms of Parkinson's disease differ from person to person. Parkinson’s disease affects the nerve cells in the brain that produce dopamine. Parkinson’s disease symptoms include muscle rigidity, tremors, and changes in speech and gait. After diagnosis, treatments can help relieve symptoms, but there is no cure.
It is estimated that 6.3 million people suffer from PD worldwide. The World Health Organization gives an "estimated crude prevalence" (the total number of existent cases each year, old and new) of 160 per 100,000, and an estimated incidence (the number of new cases each year) of 16-19 per 100,000.