It has been postulated that hair penetrates into the subcutaneous tissues through dilated hair follicles, which is thought to occur particularly in late adolescence, though follicles are not found in the walls of cysts. A sinus develops with a short tract, with a not clearly understood suction mechanism involving local anatomy, eventually leading to further penetration of the hair into the subcutaneous tissue.
Antibiotics alone do not heal a pilonidal sinus. Doctors have a number of procedures available, including the following treatments: The preferred technique for a first pilonidal sinus is incision and drainage of the sinus, removing the hair follicles, and packing the cavity with gauze. Marsupialisation - This procedure involves incision and draining, removal of pus and hair, and sewing of the edges of the fibrous tract to the wound edges. This creates an open wound that slowly covers with skin and prevents re-formation of the sinus.
Research is going on various Research Centre to get the perfect cure of this disease.
Around 50% of total population is suffering from this disease.