Definition: Premature ovarian failure- conjointly referred to as primary gonad insufficiency - refers to a loss of traditional perform of your ovaries before age forty. If your ovaries fail, they do not manufacture traditional amounts of the internal secretion oestrogen or unharness eggs often. Sterility may be a common result.
Signs and symptoms of premature female internal reproductive organ failure square measure almost like those toughened by a lady inquiring climacteric and square measure typical of steroid hormone deficiency. They include: Irregular or skipped periods (amenorrhea), could which can} be gift for years or may develop once a maternity or once stopping contraception pills: Hot flashes, Night sweats, channel condition, Irritability or problem concentrating, attenuate concupiscence
Treatment: If your periods become irregular or stop, your doctor can offer you a physical examination and raise your questions on your general health and whether or not you've got alternative symptoms of primary female internal reproductive organ insufficiency. You’ll even have a bioassay. And your blood is tested for alternative attainable causes of irregular periods. To envision for attainable female internal reproductive organ failure, your blood level of FSH (FSH) are checked. FSH signals your body to unharness associate egg monthly.
Statistics: In India, the analysis on Premature ovarian failure got the result as eighteen chromosomal anomalies were identified in POF patients (24%). Majority of the cases were found to have X-chromosome abnormalities (28%). Overall median ROS range was found to be significantly higher (P<0.01) in POF patients [50480 (120,132966) RLU/min] compared to controls [340 (120,5094) RLU/min]. Among these, 50 per cent of the POF patients had higher ROS levels, 20 per cent had medium elevation and 30 per cent were found to have normal values comparable to controls.