Toxic Hepatitis is an inflammatory disease of liver caused by exposure to certain chemicals, alcohol abuse and drugs. Common chemicals that can cause liver damage include the dry cleaning solvent carbon tetrachloride, a substance used to make plastics called vinyl chloride, and a group of industrial chemicals called polychlorinated biphenyls. In some cases, toxic hepatitis develops within hours or days of exposure to a toxin. In other cases, it may take months of regular use before signs and symptoms of toxic hepatitis appear. Nearly 119,000 cases of all-cause hepatitis were reported in India in 2012. The Integrated Disease Surveillance Program received notification of 290,000 cases of acute viral hepatitis in 2013.
People with severe symptoms are likely to receive supportive therapy in the hospital, including intravenous fluids and medication to relieve nausea and vomiting. Patients with irreversible damage to the liver may require liver transplant. Therapy is recommended for patients with fibrosis, in order to prevent disease progression, hepatic decompensation, and hepatocellular carcinoma. Patients should be advised to take prescription and nonprescription drugs only when absolutely necessary. Investigate non-drug options for common problems such as high blood pressure, high cholesterol and arthritis pain.