Typhoid fever is an infection that causes diarrhea and a rash. It is most commonly due to a type of bacterium called Salmonella typhi (S. typhi). Hospital-based studies and outbreak reports from India indicate that enteric fever is a major public health problem in this country, with Salmonella enterica serovar Typhi (S. Typhi) The 5–15 year age group there was a higher prevalence of S. typhi in blood cultures in the India. The Prevalence age group of Typhoid fever in India was 10.0 years. The incidence of typhoid among children aged 2–5 years was 340.1 in India. In India some cases were resistant to ciprofloxacin.
After the ingestion of contaminated food or water, the Salmonella bacteria invade the small intestine and enter the bloodstream temporarily. Patients develop symptoms, including fever, when the organism reenters the bloodstream. Bacteria invade the gallbladder, biliary system, and the lymphatic tissue of the bowel. Here, they multiply in high numbers. Comparative genomics study for identification of putative drug targets in Salmonella typhi Type 2, Clinical Outcome of a Portosplenomesenteric Venous Thrombosis in Necrotizing Acute Pancreatitis with Protein C and S Deficiency Treated by Anticoagulation Therapy Alone.