Pathophysiology: Viral hemorrhagic fever (VHFs) is a general term to severe group of illness caused by RNA viruses from several viral families. It is a severe multisystem syndrome caused by infectious viruses which lead to a potentially lethal disease syndrome characterized by fever, malaise, vomiting, mucosal and gastrointestinal (GI) bleeding.VHF is caused by viruses of four families: arenaviruses, filoviruses, bunyaviruses, and flaviviruses.
Disease Statistics: Crimean Congo Hemorrhagic Fever (CCHF) cases, for the first time in India, were reported from Gujarat, in January 2011. The virus (CCHF) has been found "in high quantities" in ticks collected from Ahmadabad. Scientists from the NIV (Pune) noted that the virus was openly circulating in the environment and has not been brought into India from other CCHF endemic countries.
Treatment: Patients usually receive supportive therapy but as such there are no other treatment or established cure for VHFs. Ribavirin, an anti-viral drug, have been effective in treating some individuals with Lassa fever or HFRS. Treatment with convalescent-phase plasma has been used with success in some patients with Argentine hemorrhagic fever.
Research: The research groups involved the researchers from Public Health Specialist, New Delhi, India; Department of Community Medicine, Post Graduate Institute of Medical Sciences, Rohtak, India; Department of Community Medicine, Lady Hardinge Medical College, New Delhi, India and Department of Community Medicine, Vardhman Mahavir Medical College and Safadarjung Hospital, New Delhi, India.