Hypertrophic cardiomyopathy (HCM) is the most common cause of PSCA. The overall prevalence of HCM is 1 in 500 persons, also making it a fairly common disorder. HCM tends to present in older children, and though it rarely presents in younger children, the authors report at least 1 case of presentation during infancy. Cases of HCM may occur sporadically or secondary to the inheritance of particular genetic mutations. There are now over 20 different identified HCM susceptible genes. Specific mutations in the contractile proteins of the sarcomere are associated with the development of HCM. Known genetic mutations associated with the development of HCM include myosin heavy chain 7 (MYH7), tropomyosin 1 (TPM1), myosin binding protein C (MYBPC3), troponin C type 1 (TNNC1), TNNT2, TNNI3, ACTC, MYL2, MYL3, GLA, LAMP2, and PRKAG2.
Internal Medicine Open Access, an official journal of OMICS International publishes all the articles related to Hypertrophic Cardiomyopathy. The journal is subjecting all the received manuscripts to a strict peer review process. The articles published in the journal are Open Access i.e, freely accessible to readers all around the world. Internal Medicine Open Access is maintaining the quality of articles through its strict peer review process.
Last date updated on June, 2014