Barrett’s esophagus is also called columnar epithelium lined lower oesophagus (CELLO). It is caused due to abnormal changes occur within the cell of the lower portion of the esophagus. The main reason for Barrett,s esophagus is chronic acid exposure from reflex esophagus. Mostly this kind of condition found in 5-10% patients who diagnosed for gastroesophageal reflux disease (GERD). Although, many of the patients with barrett’s esophagus do not have symptoms.
Symptoms: Barrett’s esophagus does not cause any particular symptoms, however it is associated with below mentioned symptoms. • heartburn • dysphagia • hematemesis • pain under the sternum where the esophagus meets the stomach • unintentional weight loss because eating is painful
Treatment: For barrett’s esophagus doctors will approach different types of treatment that is depend up on the severity of disease those includes medicines, Endoscopic ablative therapies, Endoscopic mucosal resection, Surgery. Doctors prefer acid supressing medicine like proton pump inhibitor; an Endoscopic ablative therapy is performing by using different methods those are Photodynamic therapy, Radiofrequency ablation; In endoscopic mucosal resection, your doctor lifts the Barrett’s tissue, injects a solution underneath or applies suction to the tissue, and then cuts the tissue off. The doctor then removes the tissue with an endoscope; many of the doctors prefer surgery because this is having very less complications.
Overall mortality was not raised in Barrett’s patients. During 7413 person years of follow up in 2373 patients there were 253 deaths (standardised mortality ratio (SMR) 96 (95% confidence interval (CI) 84–107)). Mortality from oesophageal cancer was raised in patients with specialised intestinal metaplasia (SMR 774 (95% CI 317–1231)) but only 4.7% of patients died from this cancer. Mortality from stroke (SMR 65 (95% CI 37–93)) was significantly lower than the general population while mortality from non-cancerous digestive system diseases was significantly higher (SMR 211 (95% CI 111–311)). Mortality rates from all other causes were similar to those of the general population.