Marburg virus belongs to the genus Marburgvirus in the familyFiloviridae and causes a severe hemorrhagic fever, known as Marburg hemorrhagic fever (MHF), in both humans and nonhuman primates. Marburg virus disease (MVD) (formerly known as Marburg haemorrhagic fever) was first identified in 1967 during epidemics in Marburg and Frankfurt in Germany and Belgrade in the former Yugoslavia from importation of infected monkeys from Uganda.
The initial symptoms correspond to development of viremia and include the following:
• High fever
• Abdominal pain
Generally differential diagnosis is performed for:
• Typhoid fever
• Rickettsial infections
• Acute leukemia
• Idiopathic or thrombotic thrombocytopenic purpura
The cases of viral hemorrhagic fever in the Ireland are extremely rare and usually are found in patients who recently have visited endemic areas or among those with potential occupational exposure to hemorrhagic fever viruses.