Multiple endocrine neoplasia(MEN-1) is also known as Wermer's syndrome. MEN-1 is a hereditory disorder .This type of hereditory disosorder generally passed from one generation to next generation. It affects the hormone producing glands.This disorder increases the development of tumors like cancerous and non cancerous tumors in glands.Non cancerous tumors may develop in parathyroid glands,Neuroendocrine system,anterior pituitory glands and skin. The symptoms are tiredness, bone pain, fractures and kidney stones, as well as stomach or intestinal ulcers.
The period prevalence was 0.178 × 10−5 (mean 24 year population: 1,689,588). The point prevalence was 0.219 × 10−5. Four sporadic cases were identified throughout 24 years. Three patients were alive on the prevalence day, April 21, 2012.