Posterior cortical atrophy (PCA), also called Benson's syndrome, is a form of dementia which is usually considered an atypical variant of Alzheimer's disease. The disease causes atrophy of the back (posterior) part of the cerebral cortex, resulting in the progressive disruption of complex visual processing. The disease causes atrophy of the back (posterior) part of the cerebral cortex, resulting in the progressive disruption of complex visual processing.
Although no cure for posterior cortical atrophy exists, several medications as well as many non-pharmaceutical approaches can potentially improve daily functioning and quality of life. Patients with posterior cortical atrophy can often benefit from physical and occupational therapy. Cholinesterase inhibitors approved for Alzheimer's disease, like donepezil (Aricept®), rivastigmine (Exelon®) and galantamine (Razadyne®/Reminyl®), can help the symptoms of PCA by boosting the function of brain cells to compensate for damage caused by Alzheimer's disease. Patients experiencing depression, irritability, frustration and a loss of self-confidence may benefit from antidepressant medication. statistics:In the last 3 decades, psychological factors have attracted more attention in end stage like patients with chronic renal failure. Previous researches have reported some psychological problems such as suicide ideation, depression, anxiety, sexual disorders, interpersonal problems, paranoia, physical complain, compulsive disorders, psychoses, aggression, and phobia; although researchers are not unanimous in terms of prevalence and intensity of these problems among HD patients.