Typhoid fever is a serious and potentially fatal bacterial infection. It can cause symptoms of fever, abdominal pain and constipation. If they are not treated, symptoms can rapidly get worse and lead to serious complications, such as internal bleeding. Typhoid fever is caused by bacteria called Salmonella typhi (S. typhi). It can be contracted by eating food or drinking water that has been contaminated by the S. typhi bacteria. Typhoid fever is rare in Ireland due to improvements in sanitation and public health. There were 9 cases of typhoid fever reported in Ireland in 2009. In the year 2006, 10 cases were reported in Ireland. Recent epidemological studies has shown that prevalence rate of Typhoid fever in Ireland was 0.2%.
Definitive treatment of typhoid fever (enteric fever) is based on susceptibility. Until susceptibilities are determined, antibiotics should be empiric, for which there are various recommendations. Researches are focusing on the prevention of multi-drug resistence for the effective treatment of typhoid or enteric fevers, Clinical Outcome of a Portosplenomesenteric Venous Thrombosis in Necrotizing Acute Pancreatitis with Protein C and S Deficiency Treated by Anticoagulation Therapy Alone.