alexa Is Natural Latex an Important Cause of Allergy ? | Open Access Journals
ISSN: 2155-6121
Journal of Allergy & Therapy
Like us on:
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Is Natural Latex an Important Cause of Allergy ?

Carlos Enrique Cabrera Pivaral*

Director de Educación e Investigacion, Unidad Medica de Alta Especialidad, UMAE, Hospital de Especialidades, IMSS, Jalisco

*Corresponding Author:
Carlos Enrique Cabrera Pivaral
Director de Educación e Investigacion
Unidad Medica de Alta Especialidad, UMAE
Hospital de Especialidades, IMSS, Jalisco
Tel: 36170060
E-mail: [email protected] mx

Received date: April 1, 2011; Accepted date: April 5, 2011; Published date: April 10, 2011

Citation: Pivaral CEC (2011) ¿ Is Natural Latex an Important Cause of Allergy ? J Aller Ther 2:102e. doi:10.4172/2155-6121.1000102e

Copyright: © 2011 Pivaral CEC. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Journal of Allergy & Therapy

Natural latex is an important cause of allergy in individuals with risk factors. Neuromuscular relaxants together with natural latex are among the most studied agents responsible for pre-operative anaphylaxis. Allergic reaction to latex represents, in most cases, an immune response regulated by IgE antibodies (type I hypersensitivity). This type of reaction is produced in individuals how have previously been in contact with latex and have formed sensitivity, the same as in other common forms of allergies. These types of reactions are also more frequent in certain risk groups, such as: health personnel, patients with congenital defects (spina bifida, urologic, myelomeningocele), those who have undergone multiple surgical interventions and history of repeated exposures -specially in serous and mucous- to materials such as latex. There is a known existence in patients with atrophy history, in rubber and plastic workers, janitors and patients with history of latex intolerance as: balls, balloons, gloves, preservatives, etc. There are cross reactions between latex and food antigens (bananas, cashews, avocado, celery, grenade, etc), these allergens have an antigenic action very similar to latex, clinically and immunologically [1,2].

Immunopathogenesis of allergy to latex is not completely understood. Several proteins have been identified from natural latex extracts that adhere to IgE. The main one being Hevein b 6, formed from prohevein (Hev b 6.01) and two Hevein post-transcriptional proteins (Hev b 6.02 and Hev b 6.03). These three components act like independent immunogens. In the original Heb b 6.01 protein are found regions responsible for the IgE binding, as well as the proliferative response of the T lymphocyte. Heb b 6.02 domain contains discontinuous epitopes that can recognize the B lymphocyte, while Hev b 6.03 is a better inductor of the proliferative response for having sequentiated unions to HLA-DR4 [3,4]. Though this it is possible to initiate an acquired immune response directed to immunogens, latex related proteins activated by allergenicspecific T CD+ lymphocytes. Identification of T cell dominant epitope is important and decisive for the development of a potential specific immunotherapy [5].

Clinical spectrum includes slight dermatitis cases that may or may not affect mucous, together with urticarial, pruritus and exanthema being the most frequent. Other forms in which it manifests are rhinitis respiratory profiles and bronchial obstruction. Only in rare occasions do lethal symptoms appear such as anaphylaxis, convulsions, frequently observed during anesthesia [3,4].

Pre-operative identification of high risk patients and preventive measures may decrease latex allergy and anaphilaxy incidencies [5,7].

The severity of the immediate reaction depends on the level of sensitivity and the amount of latex in which the person comes in contact with. Greatest danger of suffering extreme reactions occurs when latex comes in contact with humid areas of skin of inner parts during surgery, due to the body absorbing more quickly a larger amount of allergen, not forgetting that latex may be suspended in the air and can cause respiratory symptoms. Latex proteins may adhere to powder used in latex gloves, in using these gloves these particles together with latex allergens fly thought the air, where they can be inhaled or come in contact with the nose or the eyes and can cause symptoms.

High levels of this type of allergen dust have been measured in operating rooms. For this reason the American Society of Anesthesiologists have recommended who patients that have been identified as allergic to latex be the first to use operating rooms, which is when the concentration of these airbornallergenics (latex) is minimum, the use of non-powder or synthetic gloves is also recommended (vinyl or nitrile), reducing the risk of reaction, and the use of a physiologic solution on the gloves to remove the excess of dust [2,8-10].

For these reasons show the Natural latex is an important cause of allergy in individuals with risk factors and the most studied agents responsible for pre-operative anaphylaxis.

References

Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Recommended Conferences

Article Usage

  • Total views: 11623
  • [From(publication date):
    April-2011 - Jul 22, 2017]
  • Breakdown by view type
  • HTML page views : 7868
  • PDF downloads :3755

Review summary

  1. Sarah
    Posted on Feb 18 2017 at 9:03 am
    I was cured of HIV with the used of natural herbs. My name is Marie and am from US. I love herbs so much. Most times, injection and drugs are just a waste of time. I was cured 8months ago, i suffered from HIV for 13yrs but with the help of DR. Baba Ogu herbal medicine, i was cured within few weeks of drinking the herbs he sent to me through courier delivery service. This same doctor also cured my Aunty from herpes, as soon as i heard she had herpes, i quickly refer her to Dr. Baba Ogu and she was cured too after drinking his herbs.I have referred more than 15 persons to Dr. Baba Ogu and they were all cured from their various illness. Have you taken herbs before?. You have spent so much money on drugs,injections,surgeries etc and yet you have no good result to show for it. Contact Dr. Baba Ogu now, he is a herbalist doctor, i assured you of a cure if you drink his natural herbs. Dr Baba Ogu have herbs that cures Hiv, Herpes, diabetics, asthma, hepatitis,HBP, STD, cancer, chronic, etc. He is also a spell caster, he can cast a spell to bring back your EX lover. Contact Dr. Baba Ogu through his Email address on: [email protected] or WHATSAP/CALL him on +2348137291215. Share the good news to others once you are cured. Thank you.
 

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords